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Minimal introns are not "junky"


Yu, J; Yang, ZY; Kibukawa, M; Paddock, M; Passey, DA; Wong, GKS
2002-08
GENOME RESEARCH
Journal Article
12
8
1185-1189
Intron-size distributions for most multicellular (and some unicellular) eukaryotes have a sharp peak at their. minimal intron" size. Across the human population, these minimal introns exhibit an abundance of insertion-deletion polymorphisms, the effect of which is to maintain their optimal size. We argue that minimal introns affect function by enhancing the rate at which mRNA is exported from the cell nucleus.
COLD SPRING HARBOR LAB PRESS
SINGLE-NUCLEOTIDE POLYMORPHISMS; MESSENGER-RNA; GENOME SEQUENCE; EXPORT; GENES; RECOGNITION; EXPRESSION; MECHANISM; METAZOANS; EVOLUTION
10.1101/gr.224602
Refer to copyright notice on published article.

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Creation Date 2002-08-01 12:00:00