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Molecular and clinical aspects of apoptosis


Uren, AG; Vaux, DL
1996
PHARMACOLOGY & THERAPEUTICS
Journal Article
72
1
37-50
Unwanted cells are removed by physiological cell death processes that are highly throughout the animal kingdom. Physiological cell death plays an important role in development, tissue homeostasis and defence against viral infection and mutation. This review describes the molecular components that implement this process, the relevance of these to a variety of human diseases, and discusses the potential for novel therapies based on our understanding of them. Copyright (C) 1996 Elsevier Science Inc.
PERGAMON-ELSEVIER SCIENCE LTD
PROGRAMMED CELL-DEATH; TUMOR-NECROSIS-FACTOR; INTERLEUKIN-1-BETA CONVERTING-ENZYME; NEMATODE CAENORHABDITIS-ELEGANS; FACTOR-MEDIATED CYTOTOXICITY; BACULOVIRUS P35 PROTEIN; REQUIRE GRANZYME-B; BCL-2 HOMOLOG BAK; BONE-MARROW CELLS; T-CELLS
10.1016/S0163-7258(96)00098-8
Refer to copyright notice on published article.

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Creation Date 1996-01-01 12:00:00