EVpedia: A Community Web Portal for Extracellular Vesicles Research
Kim, DK; Lee, J; Kim, SR; Choi, DS; Yoon, YJ; Kim, JH; Go, G; Nhung, D; Hong, K; Jang, SC; Kim, SH; Park, KS; Kim, OY; Park, HT; Seo, JH; Aikawa, E; Baj-Krzyworzeka, M; van Balkom, BW; Belting, M; Blanc, L; Bond, V; Bongiovanni, A; Borras, FE; Buee, L; Buzas, EI; Cheng, L; Clayton, A; Cocucci, E; Dela Cruz, CS; Desiderio, DM; Di Vizio, D; Ekstrom, K; Falcon-Perez, JM; Gardiner, C; Giebel, B; Greening, DW; Gross, JC; Gupta, D; Hendrix, A; Hill, AF; Hill, MM; Nolte-'t Hoen, E; Hwang, DW; Inal, J; Jagannadham, MV; Jayachandran, M; Jee, YK; Jorgensen, M; Kim, KP; Kim, YK; Kislinger, T; Lasser, C; Lee, DS; Lee, H; van Leeuwen, J; Lener, T; Liu, ML; Lotvall, J; Marcilla, A; Mathivanan, S; Moller, A; Morhayim, J; Mullier, F; Nazarenko, I; Nieuwland, R; Nunes, DN; Pang, K; Park, J; Patel, T; Pocsfalvi, G; del Portillo, H; Putz, U; Ramirez, MI; Rodrigues, ML; Roh, TY; Royo, F; Sahoo, S; Schiffelers, R; Sharma, S; Siljander, P; Simpson, RJ; Soekmadji, C; Stahl, P; Stensballe, A; Stepien, E; Tahara, H; Trummer, A; Valadi, H; Vella, LJ; Wai, SN; Witwer, K; Yanez-Mo, M; Youn, H; Zeidler, R; Gho, YS
MOTIVATION: Extracellular vesicles are spherical bilayered proteolipids, harboring various bioactive molecules. Due to the complexity of the vesicular nomenclatures and components, online searches for extracellular vesicle-related publications and vesicular components are currently challenging. RESULTS: We present an improved version of EVpedia, a public database for extracellular vesicles research. This community web portal contains a database of publications and vesicular components, identification of orthologous vesicular components, bioinformatic tools, and a personalized function. EVpedia includes 6,879 publications, 172,080 vesicular components from 263 high-throughput datasets, and has been accessed >65,000 times from >750 cities. In addition, about 350 members from 73 international research groups have participated in developing EVpedia. This free web-based database might serve as a useful resource to stimulate the emerging field of extracellular vesicle research. Availability and implementation: The web site was implemented in PHP, Java, MySQL and Apache, and is freely available at http://evpedia.info. CONTACT: email@example.com.