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Cross-talk between protein synthesis, energy metabolism and autophagy in cancer


Lindqvist, LM; Tandoc, K; Topisirovic, I; Furic, L
2017-11-24
Curr Opin Genet Dev
Journal Article
48
104-111
Translation is a pivotal step in the regulation of gene expression as well as one of the most energy consuming processes in the cell. Dysregulation of translation caused by the aberrant function of upstream signaling pathways and/or perturbations in the expression or function of components of the translation machinery is frequent in cancer. In this review, we discuss emerging findings that highlight hitherto unappreciated aspects of signaling to the translation apparatus with the particular focus on emerging connections between protein synthesis, autophagy and energy homeostasis in cancer.
Elsevier
Cell Signalling and Cell Death
10.1016/j.gde.2017.11.003
29179096
Refer to copyright notice on published article.

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Creation Date 2018-01-15 09:30:04 Last Modified 2018-01-15 09:51:36