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Whole genome analysis of a schistosomiasis-transmitting freshwater snail


Adema, CM; Hillier, LW; Jones, CS; Loker, ES; Knight, M; Minx, P; Oliveira, G; Raghavan, N; Shedlock, A; do Amaral, LR; Arican-Goktas, HD; Assis, JG; Baba, EH; Baron, OL; Bayne, CJ; Bickham-Wright, U; Biggar, KK; Blouin, M; Bonning, BC; Botka, C; Bridger, JM; Buckley, KM; Buddenborg, SK; Lima Caldeira, R; Carleton, J; Carvalho, OS; Castillo, MG; Chalmers, IW; Christensens, M; Clifton, S; Cosseau, C; Coustau, C; Cripps, RM; Cuesta-Astroz, Y; Cummins, SF; di Stephano, L; Dinguirard, N; Duval, D; Emrich, S; Feschotte, C; Feyereisen, R; FitzGerald, P; Fronick, C; Fulton, L; Galinier, R; Gava, SG; Geusz, M; Geyer, KK; Giraldo-Calderon, GI; de Souza Gomes, M; Gordy, MA; Gourbal, B; Grunau, C; Hanington, PC; Hoffmann, KF; Hughes, D; Humphries, J; Jackson, DJ; Jannotti-Passos, LK; de Jesus Jeremias, W; Jobling, S; Kamel, B; Kapusta, A; Kaur, S; Koene, JM; Kohn, AB; Lawson, D; Lawton, SP; Liang, D; Limpanont, Y; Liu, S; Lockyer, AE; Lovato, TL; Ludolf, F; Magrini, V; McManus, DP; Medina, M; Misra, M; Mitta, G; Mkoji, GM; Montague, MJ; Montelongo, C; Moroz, LL; Munoz-Torres, MC; Niazi, U; Noble, LR; Oliveira, FS; Pais, FS; Papenfuss, AT; Peace, R; Pena, JJ; Pila, EA; Quelais, T; Raney, BJ; Rast, JP; Rollinson, D; Rosse, IC; Rotgans, B; Routledge, EJ; Ryan, KM; Scholte, LLS; Storey, KB; Swain, M; Tennessen, JA; Tomlinson, C; Trujillo, DL; Volpi, EV; Walker, AJ; Wang, T; Wannaporn, I; Warren, WC; Wu, XJ; Yoshino, TP; Yusuf, M; Zhang, SM; Zhao, M; Wilson, RK
2017-05-16
Nat Commun
Journal Article
8
15451
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Bioinformatics
10.1038/ncomms15451
28508897
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Creation Date 2018-01-15 09:30:19 Last Modified 2018-01-15 10:09:29