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2016
A beacon of hope in stroke therapy-blockade of pathologically activated cellular...
A beta-mannanase with a lysozyme-like fold and a novel molecular catalytic mecha...
Ablation of type-1 IFN signaling in hematopoietic cells confers protection follo...
Acetylation of the Cd8 locus by KAT6A determines memory T cell diversity
A community-based model of rapid autopsy in end-stage cancer patients
A conserved alphabeta transmembrane interface forms the core of a compact T-cell...
A conserved HIV-1-derived peptide presented by HLA-E renders infected T-cells hi...
Activation of cGAS-dependent antiviral responses by DNA intercalating agents
Acute monocytic leukemia masked by hemolytic anemia and sclerotic lesions
Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repressi...
A cytotoxic anti-IL-3Ralpha antibody targets key cells and cytokines implicated ...
ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripoten...
A minimized human insulin-receptor-binding motif revealed in a Conus geographus ...
A molecular threshold for effector CD8(+) T cell differentiation controlled by...
Anabolic androgenic steroids, an easily forgotten cause of polycythaemia and cer...
Analysis of human breast milk cells: gene expression profiles during pregnancy, ...
Analysis of local chronic inflammatory cell infiltrate combined with systemic in...
Analysis of mammalian cell proliferation and macromolecule synthesis using deute...
Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL is...
An antibody screen of a Plasmodium vivax antigen library identifies novel merozo...
A naturally occurring peptide with an elementary Single Disulfide-Directed beta-...
An immunological perspective on rheumatic heart disease pathogenesis: more quest...
A NODding acquaintance with ER stress
A novel approach to identifying patterns of human invasion-inhibitory antibodies...
A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of...
Apoptosis regulates endothelial cell number and capillary vessel diameter but no...
A rapid method to verify single-cell deposition setup for cell sorters
A single point in protein trafficking by Plasmodium falciparum determines the ex...
A SLC39A8 variant causes manganese deficiency, and glycosylation and mitochondri...
Assessing immune-related adverse events of efficacious combination immunotherapi...
A three-stage intrathymic development pathway for the mucosal-associated invaria...
A Toll-like receptor-1 variant and its characteristic cellular phenotype is asso...
Australia needs an Ombudsman or Office for Research Integrity
Autophagy and AML-food for thought
Autophagy-dependent regulatory T cells are critical for the control of graft-ver...
Autoreactive T cells in chronic spontaneous urticaria target the IgE Fc receptor...
Avenues to autoimmune arthritis triggered by diverse remote inflammatory challen...
Bach2 is required for B cell and T cell memory differentiation
BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic...
BCL-2 modifying factor promotes germ cell loss during murine oogenesis
BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only pr...
Benefit from cytoreductive nephrectomy and the prognostic role of neutrophil-to-...
BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and...
Better than nothing? Limitations of the prediction tool SecretomeP in the search...
Biallelic mutations in TMEM126B cause severe complex I deficiency with a variabl...
Biochemical and structural insights into doublecortin-like kinase domain 1
Bioinformatics analysis of sequence data
Blimp-1 controls plasma cell function through the regulation of immunoglobulin s...
Blimp-1-dependent IL-10pProduction by Tr1 cells regulates TNF-mediated tissue pa...
Cancer cell CCL5 mediates bone marrow independent angiogenesis in breast cancer
Can the cargo control the car? Mitochondrial DNA as a stimulator of TLR9-mediate...
CD271 expression on patient melanoma cells is unstable and unlinked to tumorigen...
Cell death is not essential for caspase-1-mediated interleukin-1beta activation ...
Changes in malaria burden and transmission in sentinel sites after the roll-out ...
Changes in serological immunology measures in UK and Kenyan adults post-controll...
Changes in the sympathetic innervation of the gut in rotenone treated mice as po...
Characterisation of CD4 T cells in healthy and diseased koalas (Phascolarctos ci...
Characterisation of the conformational preference and dynamics of the intrinsica...
Characterisation of the porphyromonas gingivalis manganese transport regulator o...
Characterizing Bcl-2 family protein conformation and oligomerization using cross...
Chemical chaperone TUDCA prevents apoptosis and improves survival during polymic...
Chromatin targeting: A BET inhibitor workaround
Chromosome sorting for the masses?
Circulating tumor DNA analysis detects minimal residual disease and predicts rec...
CIS is a potent checkpoint in NK cell-mediated tumor immunity
Clustered somatic mutations are frequent in transcription factor binding motifs ...
Coeliac disease: a unique model for investigating broken tolerance in autoimmuni...
Colorectal cancer atlas: An integrative resource for genomic and proteomic annot...
Combining multiple tools outperforms individual methods in gene set enrichment a...
Competition within the virus-specific CD4 T cell pool limits the T follicular he...
Complementarity and redundancy of IL-22-producing innate lymphoid cells
Comprehensive RNAi-based screening of human and mouse TLR pathways identifies sp...
Computationally designed high specificity inhibitors delineate the roles of BCL2...
Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-c...
Contextual fear conditioning induces differential alternative splicing
Cord blood monocyte-derived inflammatory cytokines suppress IL-2 and induce nonc...
Correcting gene expression data when neither the unwanted variation nor the fact...
Corrigendum to 'MicroRNAs in CD4 T cell subsets are markers of disease risk and ...
CRISPR/CAS9 - The ultimate weapon to battle infectious diseases?
Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lym...
Cryptosporidium and Giardia taxa in faecal samples from animals in catchments su...
Current challenges and novel treatment strategies in double hit lymphomas
CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
Cycloheximide can induce Bax/Bak dependent myeloid cell death independently of m...
Deciphering the innate lymphoid cell transcriptional program
Deep roots for Aboriginal Australian Y chromosomes
Deregulation of TNF expression can also cause heart valve disease
Design, synthesis, and characterization of cyclic peptidomimetics of the inducib...
Diagnosis and misdiagnosis of adult neuronal ceroid lipofuscinosis (Kufs disease...
Dicer1 mediated miRNA processing shapes the mRNA profile and function of murine ...
Differential responsiveness of innate-like IL-17- and IFN-gamma-producing gammad...
Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 col...
Differentiation and diversity of subsets in group 1 innate lymphoid cells
Different regions of Plasmodium falciparum Erythrocyte binding antigen-175 induc...
Differing rates of antibody acquisition to merozoite antigens in malaria: implic...
Digital PCR of genomic rearrangements for monitoring circulating tumour DNA
Dissecting malaria biology and epidemiology using population genetics and genomi...
Divergent transcriptional responses to physiological and xenobiotic stress in Gi...
Dominant KCNA2 mutation causes episodic ataxia and pharmacoresponsive epilepsy
Donald Metcalf 1929-2014
Donald Metcalf AC. 26 February 1929 — 15 December 2014
Doughnuts, daisy chains and crescent moons: the quest for the elusive apoptotic ...
Dual targeting of bromodomain and extra-terminal domain proteins, and WNT or MAP...
Dual targeting of EGFR: ready for prime time?
Duodenal bacteria from patients with celiac disease and healthy subjects distinc...
Dynamic changes in Id3 and E-protein activity orchestrate germinal center and pl...
Dysregulation of histone methyltransferases in breast cancer - Opportunities for...
E3 ligase E6AP represses breast cancer metastasis via regulation of ECT2-Rho sig...
Early neuroimaging markers of FOXP2 intragenic deletion
Ecology of Malaria Vectors and Current (Nongenetic) Methods of Control in the As...
Editorial: Dendritic Cell and Macrophage Nomenclature and Classification
Editorial overview: Membranes
Elementary: breast cancer culprits leave their signatures on the double helix
Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis
Emerging concepts in T follicular helper cell responses to malaria
Endothelial cell survival during angiogenesis requires the pro-survival protein ...
Enzyme mechanisms: Sugary shears
Erratum to: Measuring NLR oligomerization II: Detection of ASC speck formation b...
Essential role for a novel population of binucleated mammary epithelial cells in...
Essential role for the histone acetyltransferase KAT7 in T cell development, fit...
Essential role of the PfRh5/PfRipr/CyRPA complex during Plasmodium falciparum in...
Evaluation of non-coding variation in GLUT1 deficiency
Evolutionary divergence of the necroptosis effector MLKL
Evolution of protein quaternary structure in response to selective pressure for ...
Experimental approaches to studying the nature and impact of splicing variation ...
Exploiting the Biginelli reaction: nitrogen-rich pyrimidine-based tercyclic alph...
Exploration of the P region of PEXEL peptidomimetics leads to a potent inhibitor...
Exploring the in meso crystallization mechanism by characterizing the lipid meso...
Export of malaria proteins requires co-translational processing of the PEXEL mot...
Extending halogen-based medicinal chemistry to proteins: Iodo-Insulin as a case ...
Factors associated with insulin-induced weight gain in an Australian type 2 diab...
False economies in home-based parenteral antibiotic treatment: a health-economic...
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mech...
Focusing the spotlight on the zebrafish intestine to illuminate mechanisms of co...
FoxO3 suppresses Myc-driven lymphomagenesis
From reads to genes to pathways: differential expression analysis of RNA-Seq exp...
Functional interdependence of BRD4 and DOT1L in MLL leukemia
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-...
G-CSF and neutrophils are nonredundant mediators of murine experimental autoimmu...
Genetic basis of hindlimb loss in a naturally occurring vertebrate model
Genetic strategies to bring islet xenotransplantation to the clinic
Genomic analysis of local variation and recent evolution in Plasmodium vivax
Genomic epidemiology of artemisinin resistant malaria
Genomic resources and draft assemblies of the human and porcine varieties of sca...
German Society for Immunology and Australasian Society for Immunology joint Work...
Germline BRCA1/2 testing practices in ovarian cancer: Current state and opportun...
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndr...
G ganglioside and phosphatidylethanolamine-containing lipids are adipose tissue ...
Girdin (GIV) expression as a prognostic marker of recurrence in mismatch repair ...
Glucose- and glutamine-fueled stabilization of C-Myc is required for T-cell prol...
GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease
Granulocyte macrophage colony-stimulating factor induces CCL17 production via IR...
Granzyme M has a critical role in providing innate immune protection in ulcerati...
Growth and differentiation factors
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium...
Haemopedia: an expression atlas of murine hematopoietic cells
Health worker compliance with a 'test and treat' malaria case management protoco...
Hepatitis B virus and inhibitor of apoptosis proteins - a vulnerable liaison
Hepatitis C-induced hepatocyte apoptosis following liver transplantation is enha...
Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant...
Heterozygous mutations in HSD17B4 cause juvenile peroxisomal D-bifunctional prot...
Hierarchical phosphorylation of apical membrane antigen 1 is required for effici...
Hierarchy for targeting pro-survival BCL2 family proteins in multiple myeloma: p...
High concordance between Illumina HiSeq2500 and NextSeq500 for reduced represent...
High efficacy of primaquine treatment for Plasmodium vivax in Western Thailand
Higher-resolution structure of the human insulin receptor ectodomain: multi-moda...
High-Jaking the blood: resistance is fetal
Hobit and Blimp1 instruct a universal transcriptional program of tissue residenc...
Homo- and heterotypic association regulates signalling by the SgK269/PEAK1 and S...
How important is gametocyte clearance after malaria therapy?
HSP90 activity is required for MLKL oligomerisation and membrane translocation a...
Hydrodynamic injection as a method of gene delivery in mice: a model of chronic ...
Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged ...
Identification of an activation site in Bak and mitochondrial Bax triggered by a...
Identification of novel EZH2 targets regulating osteogenic differentiation in me...
Identity by descent fine mapping of familial adult myoclonus epilepsy (FAME) to ...
IL-12p40/IL-10 producing preCD8alpha/Clec9A+ dendritic cells are induced in neon...
IL-18 production from the NLRP1 inflammasome prevents obesity and metabolic synd...
ILC2s masquerade as ILC1s to drive chronic disease
Immunological processes underlying the slow acquisition of humoral immunity to m...
Immunomodulation by MYB is associated with tumor relapse in patients with early ...
Impact of loss of BH3-only proteins on the development and treatment of MLL-fusi...
Impact of loss of NF-kappaB1, NF-kappaB2 or c-REL on SLE-like autoimmune disease...
Impact of placental malaria and hypergammaglobulinemia on transplacental transfe...
Impact of primary tumor site on bevacizumab efficacy in metastatic colorectal ca...
Impact of surgical complications following resection of locally advanced rectal ...
Implications of Plasmodium vivax biology for control, elimination, and research
Inducible gene modification in the gastric epithelium of Tff1-CreERT2;Tff2-rtTA;...
Inductive interactions mediated by interplay of asymmetric signalling underlie d...
Infusional dose-adjusted epoch plus bortezomib for the treatment of plasmablasti...
Innate lymphoid cells: models of plasticity for immune homeostasis and rapid res...
Insane in the membrane: a structural perspective of MLKL function in necroptosis...
Insights into the naturally acquired immune response to Plasmodium vivax malaria...
In silico prioritization based on coexpression can aid epileptic encephalopathy ...
Insulin mimetic peptide disrupts the primary binding site of the insulin recepto...
Integrative analysis of subcellular quantitative proteomics studies reveals func...
Intercellular communication for innate immunity
In the Midst of Life-Cell Death: What Is It, What Is It Good for, and How to Stu...
In vivo at last. Demonstrating the biological credentials and clinical potential...
Is BOK required for apoptosis induced by endoplasmic reticulum stress?
Isoform prefiltering improves performance of count-based methods for analysis of...
Isolation and structural analysis of the covalent adduct formed between a bis-am...
It's DE-licious: a recipe for differential expression analyses of RNA-seq experi...
JAK1 Takes a FERM Hold of Type II Cytokine Receptors
Key knowledge gaps for Plasmodium vivax control and elimination
Killing Lymphoma with Smac-Mimetics: As Easy as ABC?
Lentiviral vectors to analyze cell death regulators
Life-and-Death Switches: the Rise of BH3 Mimetics
Light-activated control of protein channel assembly mediated by membrane mechani...
Limited degradation of the Plasmodium falciparum gametocyte marker pfs25 mRNA ex...
Linear ubiquitin chain assembly complex coordinates late thymic T-cell different...
Localization-based imaging of malarial antigens during red cell entry reaffirms ...
Long-lived plasma cells have a sweet tooth
Long noncoding RNA LINP1: scaffolding non-homologous end joining
Loss of a single Mcl-1 allele inhibits MYC-driven lymphomagenesis by sensitizing...
Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalli...
Loss of PUMA (BBC3) does not prevent thrombocytopenia caused by the loss of BCL-...
Malaria: Biology and disease
Malaria transmission dynamics surrounding the first nationwide long-lasting inse...
Male sterility in Mcl-1-flox mice is not due to enhanced Mcl1 protein stability
Marsupial tammar wallaby delivers milk bioactives to altricial pouch young to su...
Maternal Malaria and Malnutrition (M3) initiative, a pooled birth cohort of 13 p...
Mature IgM-expressing plasma cells sense antigen and develop competence for cyto...
MCL-1 inhibition provides a new way to suppress breast cancer metastasis and inc...
MCL-1 is required throughout B-cell development and its loss sensitizes specific...
Measuring NLR oligomerization II: Detection of ASC speck formation by confocal m...
Merozoite antigens of Plasmodium falciparum elicit strain-transcending opsonizin...
MicroRNAs in CD4 T cell subsets are markers of disease risk and T cell dysfuncti...
Microsatellite genotyping of Plasmodium vivax Isolates from pregnant women in fo...
Mitochondrial DNA from the eradicated European Plasmodium vivax and P. falciparu...
Mitochondrial genome sequence of the scabies mite provides insight into the gene...
Mitogen activated Tasmanian devil blood mononuclear cells kill devil facial tumo...
Modified thresholds for fibrosis risk scores in nonalcoholic fatty liver disease...
Monocyte- and neutrophil-derived CXCL10 impairs efficient control of blood-stage...
Monocyte-derived dendritic cells promote Th polarization, whereas conventional d...
Mouse models for gastric cancer: Matching models to biological questions
MOZ (KAT6A) is essential for the maintenance of classically defined adult hemato...
Multifunctional role of the transcription factor Blimp-1 in coordinating plasma ...
Multiple Plasmodium falciparum merozoite surface protein 1 complexes mediate mer...
Multiplex families with epilepsy: Success of clinical and molecular genetic char...
Multivariate Spearman's ρ for aggregating ranks using copulas
Murine Oncostatin M acts via Leukemia Inhibitory Factor Receptor to phosphorylat...
Naturally acquired immunity to malaria
Nephrotic syndrome as a complication of chronic graft-versus-host disease after ...
Neutralizing inhibitors in the airways of naive ferrets do not play a major role...
New insights into the regulation of innate immunity by caspase-8
NFκB1 is essential to prevent the development of multiorgan autoimmunity by limi...
NK cell-based immunotherapies: awakening the innate anti-cancer response
Novel non-canonical role of STAT1 in Natural Killer cell cytotoxicity
Olaparib maintenance therapy in patients with platinum-sensitive, relapsed serou...
Open source drug discovery with the malaria box compound collection for neglecte...
Opposing development of cytotoxic and follicular helper CD4 T cells controlled b...
Overall survival in patients with platinum-sensitive recurrent serous ovarian ca...
Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidne...
p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but...
Patient-derived xenograft (PDX) models in basic and translational breast cancer ...
PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but ...
Persistent Activation of NF-kappaB in BRCA1-Deficient Mammary Progenitors Drives...
Physiological restraint of Bak by Bcl-xL is essential for cell survival
Plasmacytoid dendritic cells are short-lived: reappraising the influence of migr...
Plasmodium merozoite TRAP family protein is essential for vacuole membrane disru...
Plasmodium vivax reticulocyte binding proteins are key targets of naturally acq...
Plasmodium vivax VIR proteins are targets of naturally-acquired antibody and T c...
Pneumocystis jirovecii pneumonia in systemic autoimmune rheumatic disease: A cas...
Polycomb repressive complex 2 is a barrier to KRAS-driven inflammation and epith...
Population genomics studies identify signatures of global dispersal and drug res...
Preparing samples for crystallization of Bcl-2 family complexes
Progress and prospects for structural studies of transmembrane interactions in s...
Progress in BCL2 inhibition for patients with chronic lymphocytic leukemia
Protective effect of inflammasome activation by hydrogen peroxide in a mouse mod...
Proteomic analysis reveals novel proteins associated with the Plasmodium protein...
Proteomic profiling of cell death: stable isotope labeling and mass spectrometry...
Proximity-based differential single-cell analysis of the niche to identify stem/...
PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia
PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progressio...
Quality of life during olaparib maintenance therapy in platinum-sensitive relaps...
Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-in...
RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in...
RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation...
Rapid inflammation in mice lacking both SOCS1 and SOCS3 in hematopoietic cells
Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and t...
Recruitment of Factor H as a Novel Complement Evasion Strategy for Blood-Stage P...
Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction
Regulation of germinal center responses, memory B cells and plasma cell formatio...
Regulation of Megakaryocyte and Platelet Survival
Regulation of platelet lifespan by apoptosis
Regulation of platelet lifespan in the presence and absence of TPO signaling
Relations between symptom severity, illness perceptions, visceral sensitivity, c...
Relative telomere lengths in tumor and normal mucosa are related to disease prog...
Removal of unwanted variation reveals novel patterns of gene expression linked t...
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Reproducibility of Illumina platform deep sequencing errors allows accurate dete...
Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E...
RIPK1 inhibits ZBP1-driven necroptosis during development
Risk factors for Plasmodium falciparum and Plasmodium vivax gametocyte carriage ...
RNA-seq analysis is easy as 1-2-3 with limma, Glimma and edgeR
Robust hyperparameter estimation protects against hypervariable genes and improv...
Role of Pro-apoptotic BH3-only proteins in Listeria monocytogenes infection
Role of the ER and Golgi in protein export by Apicomplexa
Runx1 downregulates stem cell/megakaryocytic transcription programs that support...
RUNX2 mediates plasmacytoid dendritic cell egress from the bone marrow and contr...
Safety, tolerability and pharmacokinetic properties of co-administered azithromy...
Screening strategies for TALEN-mediated gene disruption
Scribble acts as an oncogene in Emu-myc-driven lymphoma
Selective targeting of Cyclin E1 amplified high grade serous ovarian cancer by c...
Sensitive and accurate quantification of human malaria parasites using droplet d...
Separating the wheat from the chaff: systematic identification of functionally r...
Sequencing circulating cell-free DNA: the potential to refine precision cancer m...
Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role ...
Severe malaria infections impair germinal center responses by inhibiting T folli...
Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its developme...
Site-specific recombinatorics: in situ cellular barcoding with the Cre Lox syste...
Small molecules targeting Mcl-1: the search for a silver bullet in cancer therap...
SOX2 is the determining oncogenic switch in promoting lung squamous cell carcino...
SPATA2 - Keeping the TNF signal short and sweet
Spatial effects on the multiplicity of Plasmodium falciparum infections
SPSB1, a novel negative regulator of the TGF-beta signaling pathway targeting th...
statmod: Probability calculations for the Inverse Gaussian Distribution
Stochastic measurement models for quantifying lymphocyte responses using flow cy...
Stomach-specific activation of oncogenic KRAS and STAT3-dependent inflammation c...
Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acet...
Structural dissection of a complex Bacteroides ovatus gene locus conferring xylo...
Structurally conserved erythrocyte-binding domain in Plasmodium provides a versa...
Sugars and fat - A healthy way to generate functional regulatory T cells
Suppression of inflammatory disease activity in rheumatoid arthritis is associat...
Survival Impact of adjuvant chemotherapy for resected locally advanced rectal ad...
SurvivalVolume: interactive volume threshold survival graphs
Synthesis of amino heterocycle aspartyl protease inhibitors
Synthesis of an inositol hexakisphosphate (IP6) affinity probe to study the inte...
Synthesis of a tethered myo-Inositol (1,3,4,5,6)Pentakisphosphate (IP5) derivati...
Targeting apoptotic pathways to treat lymphoid malignancies
Targeting BCL-2-like proteins to kill cancer cells
Targeting BCL2 with Venetoclax in relapsed chronic lymphocytic leukemia
Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+T cell rec...
Targeting efflux pumps to overcome antifungal drug resistance
Targeting GM-CSF in inflammatory diseases
Targeting natural killer cells in cancer immunotherapy
Targeting NK cells for anticancer immunotherapy: clinical and preclinical approa...
Targeting p38 or MK2 enhances the anti-leukemic activity of smac-mimetics
Targeting plasma cells: are we any closer to a panacea for diseases of antibody-...
T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvir...
T-cell stimuli independently sum to regulate an inherited clonal division fate
Ten simple rules for a bioinformatics journal club
TGF-beta inhibits the activation and functions of NK cells by repressing the mTO...
Th17 cell differentiation proceeds independently of IRF8
The A2b adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation...
The association between naturally acquired IgG subclass specific antibodies to t...
The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cel...
The BECN1 N-terminal domain is intrinsically disordered
The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to i...
The complexities and caveats of lineage tracing in the mammary gland
The effects of Cis-regulatory mutations in the SUL1 gene on sulfate-limited fitn...
The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain
The evolution of innate lymphoid cells
The evolving world of pseudoenzymes: proteins, prejudice and zombies
The expanding spectrum of NFkB1 deficiency
The Helix-Loop-Helix protein ID2 governs NK cell fate by tuning their sensitivit...
The highway to hell: A RIP kinase-directed shortcut to inflammatory cytokine pro...
The hinge domain of the epigenetic repressor, Smchd1, adopts an unconventional h...
The HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 haplotype protects autoantibody-positiv...
The identification of immune genes in the milk transcriptome of the Tasmanian de...
The impact of bevacizumab in metastatic colorectal cancer with an intact primary...
The importance of being chaperoned: HSP90 and necroptosis
The incidence and differential seasonal patterns of Plasmodium vivax primary inf...
The intersection of cell death and inflammasome activation
The isolation and enrichment of large numbers of highly purified mouse spleen de...
The JAK–STAT–SOCS signaling cascade
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
The modern interleukin-1 superfamily: Divergent roles in obesity
The new editor-targeted genome engineering in the absence of homology-directed r...
The NF-kappaB transcription factor RelA is required for the tolerogenic function...
The pseudokinase MLKL and the kinase RIPK3 have distinct roles in autoimmune dis...
The pseudokinase MLKL mediates programmed hepatocellular necrosis independently ...
Therapeutic response to non-genotoxic activation of p53 by nutlin3a is driven by...
Therapeutic targeting of the G-CSF receptor reduces neutrophil trafficking and j...
The transcription factor ASCIZ and its target DYNLL1 are essential for the devel...
The ubiquitin ligase E6AP mediates nonproteolytic polyubiquitylation of beta-cat...
The use of ipilimumab in patients with rheumatoid arthritis and metastatic melan...
The UT family of MHC class I loci unique to non-eutherian mammals has limited po...
Thirty years of BCL-2: translating cell death discoveries into novel cancer ther...
Three-dimensional disorganisation of the cancer genome occurs coincident with lo...
Time-course study of the transcriptome of peripheral blood mononuclear cells (PB...
Tissue-specific designs of stem cell hierarchies
Total synthesis of a biotinylated rocaglate: Selective targeting of the translat...
Transcriptional profiling of the epigenetic regulator Smchd1
Transformed lymphoma
Transforming growth factor-beta and Notch ligands act as opposing environmental ...
Transketolase-like 1 ectopic expression is associated with DNA hypomethylation a...
Transmissible cancers in an evolutionary context
Truncated latrunculins as actin inhibitors targeting Plasmodium falciparum motil...
Tumor-suppressor functions of the TP53 pathway
Type 1 innate lymphoid cell biology: lessons learnt from natural killer cells
Type I interferons direct gammaherpesvirus host colonization
Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expressi...
Using CRISPR/Cas9 technology for manipulating cell death regulators
Using human pluripotent stem cells to study Friedreich ataxia cardiomyopathy
Vaccine development
Variation in relapse frequency and the transmission potential of Plasmodium viva...
Venetoclax responses of pediatric ALL xenografts reveal MLLr ALL sensitivity, bu...
YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfol...
2016
A beacon of hope in stroke therapy-blockade of pathologically activated cellular...
A beta-mannanase with a lysozyme-like fold and a novel molecular catalytic mecha...
Ablation of type-1 IFN signaling in hematopoietic cells confers protection follo...
Acetylation of the Cd8 locus by KAT6A determines memory T cell diversity
A community-based model of rapid autopsy in end-stage cancer patients
A conserved alphabeta transmembrane interface forms the core of a compact T-cell...
A conserved HIV-1-derived peptide presented by HLA-E renders infected T-cells hi...
Activation of cGAS-dependent antiviral responses by DNA intercalating agents
Acute monocytic leukemia masked by hemolytic anemia and sclerotic lesions
Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repressi...
A cytotoxic anti-IL-3Ralpha antibody targets key cells and cytokines implicated ...
ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripoten...
A minimized human insulin-receptor-binding motif revealed in a Conus geographus ...
A molecular threshold for effector CD8(+) T cell differentiation controlled by...
Anabolic androgenic steroids, an easily forgotten cause of polycythaemia and cer...
Analysis of human breast milk cells: gene expression profiles during pregnancy, ...
Analysis of local chronic inflammatory cell infiltrate combined with systemic in...
Analysis of mammalian cell proliferation and macromolecule synthesis using deute...
Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL is...
An antibody screen of a Plasmodium vivax antigen library identifies novel merozo...
A naturally occurring peptide with an elementary Single Disulfide-Directed beta-...
An immunological perspective on rheumatic heart disease pathogenesis: more quest...
A NODding acquaintance with ER stress
A novel approach to identifying patterns of human invasion-inhibitory antibodies...
A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of...
Apoptosis regulates endothelial cell number and capillary vessel diameter but no...
A rapid method to verify single-cell deposition setup for cell sorters
A single point in protein trafficking by Plasmodium falciparum determines the ex...
A SLC39A8 variant causes manganese deficiency, and glycosylation and mitochondri...
Assessing immune-related adverse events of efficacious combination immunotherapi...
A three-stage intrathymic development pathway for the mucosal-associated invaria...
A Toll-like receptor-1 variant and its characteristic cellular phenotype is asso...
Australia needs an Ombudsman or Office for Research Integrity
Autophagy and AML-food for thought
Autophagy-dependent regulatory T cells are critical for the control of graft-ver...
Autoreactive T cells in chronic spontaneous urticaria target the IgE Fc receptor...
Avenues to autoimmune arthritis triggered by diverse remote inflammatory challen...
Bach2 is required for B cell and T cell memory differentiation
BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic...
BCL-2 modifying factor promotes germ cell loss during murine oogenesis
BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only pr...
Benefit from cytoreductive nephrectomy and the prognostic role of neutrophil-to-...
BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and...
Better than nothing? Limitations of the prediction tool SecretomeP in the search...
Biallelic mutations in TMEM126B cause severe complex I deficiency with a variabl...
Biochemical and structural insights into doublecortin-like kinase domain 1
Bioinformatics analysis of sequence data
Blimp-1 controls plasma cell function through the regulation of immunoglobulin s...
Blimp-1-dependent IL-10pProduction by Tr1 cells regulates TNF-mediated tissue pa...
Cancer cell CCL5 mediates bone marrow independent angiogenesis in breast cancer
Can the cargo control the car? Mitochondrial DNA as a stimulator of TLR9-mediate...
CD271 expression on patient melanoma cells is unstable and unlinked to tumorigen...
Cell death is not essential for caspase-1-mediated interleukin-1beta activation ...
Changes in malaria burden and transmission in sentinel sites after the roll-out ...
Changes in serological immunology measures in UK and Kenyan adults post-controll...
Changes in the sympathetic innervation of the gut in rotenone treated mice as po...
Characterisation of CD4 T cells in healthy and diseased koalas (Phascolarctos ci...
Characterisation of the conformational preference and dynamics of the intrinsica...
Characterisation of the porphyromonas gingivalis manganese transport regulator o...
Characterizing Bcl-2 family protein conformation and oligomerization using cross...
Chemical chaperone TUDCA prevents apoptosis and improves survival during polymic...
Chromatin targeting: A BET inhibitor workaround
Chromosome sorting for the masses?
Circulating tumor DNA analysis detects minimal residual disease and predicts rec...
CIS is a potent checkpoint in NK cell-mediated tumor immunity
Clustered somatic mutations are frequent in transcription factor binding motifs ...
Coeliac disease: a unique model for investigating broken tolerance in autoimmuni...
Colorectal cancer atlas: An integrative resource for genomic and proteomic annot...
Combining multiple tools outperforms individual methods in gene set enrichment a...
Competition within the virus-specific CD4 T cell pool limits the T follicular he...
Complementarity and redundancy of IL-22-producing innate lymphoid cells
Comprehensive RNAi-based screening of human and mouse TLR pathways identifies sp...
Computationally designed high specificity inhibitors delineate the roles of BCL2...
Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-c...
Contextual fear conditioning induces differential alternative splicing
Cord blood monocyte-derived inflammatory cytokines suppress IL-2 and induce nonc...
Correcting gene expression data when neither the unwanted variation nor the fact...
Corrigendum to 'MicroRNAs in CD4 T cell subsets are markers of disease risk and ...
CRISPR/CAS9 - The ultimate weapon to battle infectious diseases?
Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lym...
Cryptosporidium and Giardia taxa in faecal samples from animals in catchments su...
Current challenges and novel treatment strategies in double hit lymphomas
CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
Cycloheximide can induce Bax/Bak dependent myeloid cell death independently of m...
Deciphering the innate lymphoid cell transcriptional program
Deep roots for Aboriginal Australian Y chromosomes
Deregulation of TNF expression can also cause heart valve disease
Design, synthesis, and characterization of cyclic peptidomimetics of the inducib...
Diagnosis and misdiagnosis of adult neuronal ceroid lipofuscinosis (Kufs disease...
Dicer1 mediated miRNA processing shapes the mRNA profile and function of murine ...
Differential responsiveness of innate-like IL-17- and IFN-gamma-producing gammad...
Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 col...
Differentiation and diversity of subsets in group 1 innate lymphoid cells
Different regions of Plasmodium falciparum Erythrocyte binding antigen-175 induc...
Differing rates of antibody acquisition to merozoite antigens in malaria: implic...
Digital PCR of genomic rearrangements for monitoring circulating tumour DNA
Dissecting malaria biology and epidemiology using population genetics and genomi...
Divergent transcriptional responses to physiological and xenobiotic stress in Gi...
Dominant KCNA2 mutation causes episodic ataxia and pharmacoresponsive epilepsy
Donald Metcalf 1929-2014
Donald Metcalf AC. 26 February 1929 — 15 December 2014
Doughnuts, daisy chains and crescent moons: the quest for the elusive apoptotic ...
Dual targeting of bromodomain and extra-terminal domain proteins, and WNT or MAP...
Dual targeting of EGFR: ready for prime time?
Duodenal bacteria from patients with celiac disease and healthy subjects distinc...
Dynamic changes in Id3 and E-protein activity orchestrate germinal center and pl...
Dysregulation of histone methyltransferases in breast cancer - Opportunities for...
E3 ligase E6AP represses breast cancer metastasis via regulation of ECT2-Rho sig...
Early neuroimaging markers of FOXP2 intragenic deletion
Ecology of Malaria Vectors and Current (Nongenetic) Methods of Control in the As...
Editorial: Dendritic Cell and Macrophage Nomenclature and Classification
Editorial overview: Membranes
Elementary: breast cancer culprits leave their signatures on the double helix
Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis
Emerging concepts in T follicular helper cell responses to malaria
Endothelial cell survival during angiogenesis requires the pro-survival protein ...
Enzyme mechanisms: Sugary shears
Erratum to: Measuring NLR oligomerization II: Detection of ASC speck formation b...
Essential role for a novel population of binucleated mammary epithelial cells in...
Essential role for the histone acetyltransferase KAT7 in T cell development, fit...
Essential role of the PfRh5/PfRipr/CyRPA complex during Plasmodium falciparum in...
Evaluation of non-coding variation in GLUT1 deficiency
Evolutionary divergence of the necroptosis effector MLKL
Evolution of protein quaternary structure in response to selective pressure for ...
Experimental approaches to studying the nature and impact of splicing variation ...
Exploiting the Biginelli reaction: nitrogen-rich pyrimidine-based tercyclic alph...
Exploration of the P region of PEXEL peptidomimetics leads to a potent inhibitor...
Exploring the in meso crystallization mechanism by characterizing the lipid meso...
Export of malaria proteins requires co-translational processing of the PEXEL mot...
Extending halogen-based medicinal chemistry to proteins: Iodo-Insulin as a case ...
Factors associated with insulin-induced weight gain in an Australian type 2 diab...
False economies in home-based parenteral antibiotic treatment: a health-economic...
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mech...
Focusing the spotlight on the zebrafish intestine to illuminate mechanisms of co...
FoxO3 suppresses Myc-driven lymphomagenesis
From reads to genes to pathways: differential expression analysis of RNA-Seq exp...
Functional interdependence of BRD4 and DOT1L in MLL leukemia
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-...
G-CSF and neutrophils are nonredundant mediators of murine experimental autoimmu...
Genetic basis of hindlimb loss in a naturally occurring vertebrate model
Genetic strategies to bring islet xenotransplantation to the clinic
Genomic analysis of local variation and recent evolution in Plasmodium vivax
Genomic epidemiology of artemisinin resistant malaria
Genomic resources and draft assemblies of the human and porcine varieties of sca...
German Society for Immunology and Australasian Society for Immunology joint Work...
Germline BRCA1/2 testing practices in ovarian cancer: Current state and opportun...
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndr...
G ganglioside and phosphatidylethanolamine-containing lipids are adipose tissue ...
Girdin (GIV) expression as a prognostic marker of recurrence in mismatch repair ...
Glucose- and glutamine-fueled stabilization of C-Myc is required for T-cell prol...
GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease
Granulocyte macrophage colony-stimulating factor induces CCL17 production via IR...
Granzyme M has a critical role in providing innate immune protection in ulcerati...
Growth and differentiation factors
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium...
Haemopedia: an expression atlas of murine hematopoietic cells
Health worker compliance with a 'test and treat' malaria case management protoco...
Hepatitis B virus and inhibitor of apoptosis proteins - a vulnerable liaison
Hepatitis C-induced hepatocyte apoptosis following liver transplantation is enha...
Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant...
Heterozygous mutations in HSD17B4 cause juvenile peroxisomal D-bifunctional prot...
Hierarchical phosphorylation of apical membrane antigen 1 is required for effici...
Hierarchy for targeting pro-survival BCL2 family proteins in multiple myeloma: p...
High concordance between Illumina HiSeq2500 and NextSeq500 for reduced represent...
High efficacy of primaquine treatment for Plasmodium vivax in Western Thailand
Higher-resolution structure of the human insulin receptor ectodomain: multi-moda...
High-Jaking the blood: resistance is fetal
Hobit and Blimp1 instruct a universal transcriptional program of tissue residenc...
Homo- and heterotypic association regulates signalling by the SgK269/PEAK1 and S...
How important is gametocyte clearance after malaria therapy?
HSP90 activity is required for MLKL oligomerisation and membrane translocation a...
Hydrodynamic injection as a method of gene delivery in mice: a model of chronic ...
Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged ...
Identification of an activation site in Bak and mitochondrial Bax triggered by a...
Identification of novel EZH2 targets regulating osteogenic differentiation in me...
Identity by descent fine mapping of familial adult myoclonus epilepsy (FAME) to ...
IL-12p40/IL-10 producing preCD8alpha/Clec9A+ dendritic cells are induced in neon...
IL-18 production from the NLRP1 inflammasome prevents obesity and metabolic synd...
ILC2s masquerade as ILC1s to drive chronic disease
Immunological processes underlying the slow acquisition of humoral immunity to m...
Immunomodulation by MYB is associated with tumor relapse in patients with early ...
Impact of loss of BH3-only proteins on the development and treatment of MLL-fusi...
Impact of loss of NF-kappaB1, NF-kappaB2 or c-REL on SLE-like autoimmune disease...
Impact of placental malaria and hypergammaglobulinemia on transplacental transfe...
Impact of primary tumor site on bevacizumab efficacy in metastatic colorectal ca...
Impact of surgical complications following resection of locally advanced rectal ...
Implications of Plasmodium vivax biology for control, elimination, and research
Inducible gene modification in the gastric epithelium of Tff1-CreERT2;Tff2-rtTA;...
Inductive interactions mediated by interplay of asymmetric signalling underlie d...
Infusional dose-adjusted epoch plus bortezomib for the treatment of plasmablasti...
Innate lymphoid cells: models of plasticity for immune homeostasis and rapid res...
Insane in the membrane: a structural perspective of MLKL function in necroptosis...
Insights into the naturally acquired immune response to Plasmodium vivax malaria...
In silico prioritization based on coexpression can aid epileptic encephalopathy ...
Insulin mimetic peptide disrupts the primary binding site of the insulin recepto...
Integrative analysis of subcellular quantitative proteomics studies reveals func...
Intercellular communication for innate immunity
In the Midst of Life-Cell Death: What Is It, What Is It Good for, and How to Stu...
In vivo at last. Demonstrating the biological credentials and clinical potential...
Is BOK required for apoptosis induced by endoplasmic reticulum stress?
Isoform prefiltering improves performance of count-based methods for analysis of...
Isolation and structural analysis of the covalent adduct formed between a bis-am...
It's DE-licious: a recipe for differential expression analyses of RNA-seq experi...
JAK1 Takes a FERM Hold of Type II Cytokine Receptors
Key knowledge gaps for Plasmodium vivax control and elimination
Killing Lymphoma with Smac-Mimetics: As Easy as ABC?
Lentiviral vectors to analyze cell death regulators
Life-and-Death Switches: the Rise of BH3 Mimetics
Light-activated control of protein channel assembly mediated by membrane mechani...
Limited degradation of the Plasmodium falciparum gametocyte marker pfs25 mRNA ex...
Linear ubiquitin chain assembly complex coordinates late thymic T-cell different...
Localization-based imaging of malarial antigens during red cell entry reaffirms ...
Long-lived plasma cells have a sweet tooth
Long noncoding RNA LINP1: scaffolding non-homologous end joining
Loss of a single Mcl-1 allele inhibits MYC-driven lymphomagenesis by sensitizing...
Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalli...
Loss of PUMA (BBC3) does not prevent thrombocytopenia caused by the loss of BCL-...
Malaria: Biology and disease
Malaria transmission dynamics surrounding the first nationwide long-lasting inse...
Male sterility in Mcl-1-flox mice is not due to enhanced Mcl1 protein stability
Marsupial tammar wallaby delivers milk bioactives to altricial pouch young to su...
Maternal Malaria and Malnutrition (M3) initiative, a pooled birth cohort of 13 p...
Mature IgM-expressing plasma cells sense antigen and develop competence for cyto...
MCL-1 inhibition provides a new way to suppress breast cancer metastasis and inc...
MCL-1 is required throughout B-cell development and its loss sensitizes specific...
Measuring NLR oligomerization II: Detection of ASC speck formation by confocal m...
Merozoite antigens of Plasmodium falciparum elicit strain-transcending opsonizin...
MicroRNAs in CD4 T cell subsets are markers of disease risk and T cell dysfuncti...
Microsatellite genotyping of Plasmodium vivax Isolates from pregnant women in fo...
Mitochondrial DNA from the eradicated European Plasmodium vivax and P. falciparu...
Mitochondrial genome sequence of the scabies mite provides insight into the gene...
Mitogen activated Tasmanian devil blood mononuclear cells kill devil facial tumo...
Modified thresholds for fibrosis risk scores in nonalcoholic fatty liver disease...
Monocyte- and neutrophil-derived CXCL10 impairs efficient control of blood-stage...
Monocyte-derived dendritic cells promote Th polarization, whereas conventional d...
Mouse models for gastric cancer: Matching models to biological questions
MOZ (KAT6A) is essential for the maintenance of classically defined adult hemato...
Multifunctional role of the transcription factor Blimp-1 in coordinating plasma ...
Multiple Plasmodium falciparum merozoite surface protein 1 complexes mediate mer...
Multiplex families with epilepsy: Success of clinical and molecular genetic char...
Multivariate Spearman's ρ for aggregating ranks using copulas
Murine Oncostatin M acts via Leukemia Inhibitory Factor Receptor to phosphorylat...
Naturally acquired immunity to malaria
Nephrotic syndrome as a complication of chronic graft-versus-host disease after ...
Neutralizing inhibitors in the airways of naive ferrets do not play a major role...
New insights into the regulation of innate immunity by caspase-8
NFκB1 is essential to prevent the development of multiorgan autoimmunity by limi...
NK cell-based immunotherapies: awakening the innate anti-cancer response
Novel non-canonical role of STAT1 in Natural Killer cell cytotoxicity
Olaparib maintenance therapy in patients with platinum-sensitive, relapsed serou...
Open source drug discovery with the malaria box compound collection for neglecte...
Opposing development of cytotoxic and follicular helper CD4 T cells controlled b...
Overall survival in patients with platinum-sensitive recurrent serous ovarian ca...
Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidne...
p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but...
Patient-derived xenograft (PDX) models in basic and translational breast cancer ...
PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but ...
Persistent Activation of NF-kappaB in BRCA1-Deficient Mammary Progenitors Drives...
Physiological restraint of Bak by Bcl-xL is essential for cell survival
Plasmacytoid dendritic cells are short-lived: reappraising the influence of migr...
Plasmodium merozoite TRAP family protein is essential for vacuole membrane disru...
Plasmodium vivax reticulocyte binding proteins are key targets of naturally acq...
Plasmodium vivax VIR proteins are targets of naturally-acquired antibody and T c...
Pneumocystis jirovecii pneumonia in systemic autoimmune rheumatic disease: A cas...
Polycomb repressive complex 2 is a barrier to KRAS-driven inflammation and epith...
Population genomics studies identify signatures of global dispersal and drug res...
Preparing samples for crystallization of Bcl-2 family complexes
Progress and prospects for structural studies of transmembrane interactions in s...
Progress in BCL2 inhibition for patients with chronic lymphocytic leukemia
Protective effect of inflammasome activation by hydrogen peroxide in a mouse mod...
Proteomic analysis reveals novel proteins associated with the Plasmodium protein...
Proteomic profiling of cell death: stable isotope labeling and mass spectrometry...
Proximity-based differential single-cell analysis of the niche to identify stem/...
PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia
PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progressio...
Quality of life during olaparib maintenance therapy in platinum-sensitive relaps...
Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-in...
RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in...
RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation...
Rapid inflammation in mice lacking both SOCS1 and SOCS3 in hematopoietic cells
Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and t...
Recruitment of Factor H as a Novel Complement Evasion Strategy for Blood-Stage P...
Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction
Regulation of germinal center responses, memory B cells and plasma cell formatio...
Regulation of Megakaryocyte and Platelet Survival
Regulation of platelet lifespan by apoptosis
Regulation of platelet lifespan in the presence and absence of TPO signaling
Relations between symptom severity, illness perceptions, visceral sensitivity, c...
Relative telomere lengths in tumor and normal mucosa are related to disease prog...
Removal of unwanted variation reveals novel patterns of gene expression linked t...
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Reproducibility of Illumina platform deep sequencing errors allows accurate dete...
Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E...
RIPK1 inhibits ZBP1-driven necroptosis during development
Risk factors for Plasmodium falciparum and Plasmodium vivax gametocyte carriage ...
RNA-seq analysis is easy as 1-2-3 with limma, Glimma and edgeR
Robust hyperparameter estimation protects against hypervariable genes and improv...
Role of Pro-apoptotic BH3-only proteins in Listeria monocytogenes infection
Role of the ER and Golgi in protein export by Apicomplexa
Runx1 downregulates stem cell/megakaryocytic transcription programs that support...
RUNX2 mediates plasmacytoid dendritic cell egress from the bone marrow and contr...
Safety, tolerability and pharmacokinetic properties of co-administered azithromy...
Screening strategies for TALEN-mediated gene disruption
Scribble acts as an oncogene in Emu-myc-driven lymphoma
Selective targeting of Cyclin E1 amplified high grade serous ovarian cancer by c...
Sensitive and accurate quantification of human malaria parasites using droplet d...
Separating the wheat from the chaff: systematic identification of functionally r...
Sequencing circulating cell-free DNA: the potential to refine precision cancer m...
Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role ...
Severe malaria infections impair germinal center responses by inhibiting T folli...
Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its developme...
Site-specific recombinatorics: in situ cellular barcoding with the Cre Lox syste...
Small molecules targeting Mcl-1: the search for a silver bullet in cancer therap...
SOX2 is the determining oncogenic switch in promoting lung squamous cell carcino...
SPATA2 - Keeping the TNF signal short and sweet
Spatial effects on the multiplicity of Plasmodium falciparum infections
SPSB1, a novel negative regulator of the TGF-beta signaling pathway targeting th...
statmod: Probability calculations for the Inverse Gaussian Distribution
Stochastic measurement models for quantifying lymphocyte responses using flow cy...
Stomach-specific activation of oncogenic KRAS and STAT3-dependent inflammation c...
Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acet...
Structural dissection of a complex Bacteroides ovatus gene locus conferring xylo...
Structurally conserved erythrocyte-binding domain in Plasmodium provides a versa...
Sugars and fat - A healthy way to generate functional regulatory T cells
Suppression of inflammatory disease activity in rheumatoid arthritis is associat...
Survival Impact of adjuvant chemotherapy for resected locally advanced rectal ad...
SurvivalVolume: interactive volume threshold survival graphs
Synthesis of amino heterocycle aspartyl protease inhibitors
Synthesis of an inositol hexakisphosphate (IP6) affinity probe to study the inte...
Synthesis of a tethered myo-Inositol (1,3,4,5,6)Pentakisphosphate (IP5) derivati...
Targeting apoptotic pathways to treat lymphoid malignancies
Targeting BCL-2-like proteins to kill cancer cells
Targeting BCL2 with Venetoclax in relapsed chronic lymphocytic leukemia
Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+T cell rec...
Targeting efflux pumps to overcome antifungal drug resistance
Targeting GM-CSF in inflammatory diseases
Targeting natural killer cells in cancer immunotherapy
Targeting NK cells for anticancer immunotherapy: clinical and preclinical approa...
Targeting p38 or MK2 enhances the anti-leukemic activity of smac-mimetics
Targeting plasma cells: are we any closer to a panacea for diseases of antibody-...
T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvir...
T-cell stimuli independently sum to regulate an inherited clonal division fate
Ten simple rules for a bioinformatics journal club
TGF-beta inhibits the activation and functions of NK cells by repressing the mTO...
Th17 cell differentiation proceeds independently of IRF8
The A2b adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation...
The association between naturally acquired IgG subclass specific antibodies to t...
The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cel...
The BECN1 N-terminal domain is intrinsically disordered
The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to i...
The complexities and caveats of lineage tracing in the mammary gland
The effects of Cis-regulatory mutations in the SUL1 gene on sulfate-limited fitn...
The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain
The evolution of innate lymphoid cells
The evolving world of pseudoenzymes: proteins, prejudice and zombies
The expanding spectrum of NFkB1 deficiency
The Helix-Loop-Helix protein ID2 governs NK cell fate by tuning their sensitivit...
The highway to hell: A RIP kinase-directed shortcut to inflammatory cytokine pro...
The hinge domain of the epigenetic repressor, Smchd1, adopts an unconventional h...
The HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 haplotype protects autoantibody-positiv...
The identification of immune genes in the milk transcriptome of the Tasmanian de...
The impact of bevacizumab in metastatic colorectal cancer with an intact primary...
The importance of being chaperoned: HSP90 and necroptosis
The incidence and differential seasonal patterns of Plasmodium vivax primary inf...
The intersection of cell death and inflammasome activation
The isolation and enrichment of large numbers of highly purified mouse spleen de...
The JAK–STAT–SOCS signaling cascade
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
The modern interleukin-1 superfamily: Divergent roles in obesity
The new editor-targeted genome engineering in the absence of homology-directed r...
The NF-kappaB transcription factor RelA is required for the tolerogenic function...
The pseudokinase MLKL and the kinase RIPK3 have distinct roles in autoimmune dis...
The pseudokinase MLKL mediates programmed hepatocellular necrosis independently ...
Therapeutic response to non-genotoxic activation of p53 by nutlin3a is driven by...
Therapeutic targeting of the G-CSF receptor reduces neutrophil trafficking and j...
The transcription factor ASCIZ and its target DYNLL1 are essential for the devel...
The ubiquitin ligase E6AP mediates nonproteolytic polyubiquitylation of beta-cat...
The use of ipilimumab in patients with rheumatoid arthritis and metastatic melan...
The UT family of MHC class I loci unique to non-eutherian mammals has limited po...
Thirty years of BCL-2: translating cell death discoveries into novel cancer ther...
Three-dimensional disorganisation of the cancer genome occurs coincident with lo...
Time-course study of the transcriptome of peripheral blood mononuclear cells (PB...
Tissue-specific designs of stem cell hierarchies
Total synthesis of a biotinylated rocaglate: Selective targeting of the translat...
Transcriptional profiling of the epigenetic regulator Smchd1
Transformed lymphoma
Transforming growth factor-beta and Notch ligands act as opposing environmental ...
Transketolase-like 1 ectopic expression is associated with DNA hypomethylation a...
Transmissible cancers in an evolutionary context
Truncated latrunculins as actin inhibitors targeting Plasmodium falciparum motil...
Tumor-suppressor functions of the TP53 pathway
Type 1 innate lymphoid cell biology: lessons learnt from natural killer cells
Type I interferons direct gammaherpesvirus host colonization
Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expressi...
Using CRISPR/Cas9 technology for manipulating cell death regulators
Using human pluripotent stem cells to study Friedreich ataxia cardiomyopathy
Vaccine development
Variation in relapse frequency and the transmission potential of Plasmodium viva...
Venetoclax responses of pediatric ALL xenografts reveal MLLr ALL sensitivity, bu...
YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfol...