Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart
Details
Publication Year 1998-04, Volume 73, Issue #1, Page 125-127
Journal Title
MECHANISMS OF DEVELOPMENT
Publication Type
Journal Article
Abstract
NK-2 class homeobox genes are candidate patterning and lineage regulators in diverse organisms. We report here the embryonic expression pattern of murine member, Nkx2-6. In keeping with its vertebrate relatives, Nkx2-6 was transcribed in ventrolateral embryonic structures. Expression was first detected at E8.0 in endodermal walls of the foregut pocket, tissue destined to become pharyngeal floor. From E8.0-10.5, transcripts were concentrated in pharyngeal pouches and juxtaposed arch ectoderm and mesoderm, as well as in more caudal gut segments. Expression was also seen at opposite poles of the developing heart: from E8-8.5 in posterior myocardial progenitors, then sinus venosa and dorsal pericardium, and from E9.5 in outflow tract myocardium. (C) 1998 Elsevier Science Ireland Ltd.
Publisher
ELSEVIER SCIENCE BV
Rights Notice
Refer to copyright notice on published article.


Creation Date: 1998-04-01 12:00:00
Last Modified: 0001-01-01 12:00:00
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