The regulation and roles of Rel/NF-kappa B transcription factors during lymphocyte activation
- Author(s)
- Gerondakis, S; Grumont, R; Rourke, I; Grossmann, M;
- Details
- Publication Year 1998-06,Volume 10,Issue #3,Page 353-359
- Journal Title
- CURRENT OPINION IN IMMUNOLOGY
- Publication Type
- Journal Article
- Abstract
- The activation of B and T cells by a wide range of stimuli can rapidly induce specific gene expression via a mechanism that promotes the nuclear translocation of different Rel/nuclear factor-kappa B (NF-kappa B) transcription factors which are normally resident in the cytoplasm. Recent findings highlight the crucial roles of specific Rel/NF-kappa B family members in the processes of cell division, apoptosis and differentiation that accompany lymphocyte activation.
- Publisher
- CURRENT BIOLOGY LTD
- Keywords
- EXHIBIT DEFECTS; CELLS; ALPHA; MICE; CD28; PROLIFERATION; EXPRESSION; PROTEINS; BINDING; BETA
- Publisher's Version
- https://doi.org/10.1016/S0952-7915(98)80175-1
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1998-06-01 12:00:00