A portrait of the Bcl-2 protein family: Life, death, and the whole picture
- Author(s)
- Pellegrini, M; Strasser, A;
- Details
- Publication Year 1999-11,Volume 19,Issue #6,Page 365-377
- Journal Title
- JOURNAL OF CLINICAL IMMUNOLOGY
- Publication Type
- Journal Article
- Abstract
- The Bcl-2 family of proteins are important regulators of cell death. They are comprised of two opposing factions, the proapoptotic versus the antiapoptotic members. Both are required for normal development and cellular homeostasis of the immune system and other tissues. However, in certain circumstances they may participate in the development of disease.
- Publisher
- KLUWER ACADEMIC/PLENUM PUBL
- Keywords
- INDUCED CELL-DEATH; TUMOR-NECROSIS-FACTOR; AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; SURVIVAL-PROMOTING PROTEINS; RECEPTOR-DEFICIENT MICE; BLOOD MONONUCLEAR-CELLS; INHIBITS MULTIPLE FORMS; FAS GENE-MUTATIONS; T-CELL; TRANSGENIC MICE
- Publisher's Version
- https://doi.org/10.1023/A:1020598632068
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1999-11-01 12:00:00