LOCALIZATION OF 2 MOUSE GENES ENCODING THE PROTEIN-TYROSINE KINASE RECEPTOR-RELATED PROTEIN RYK
- Author(s)
- Gough, NM; Rakar, S; Hovens, CM; Wilks, A;
- Details
- Publication Year 1995-04,Volume 6,Issue #4,Page 255-256
- Journal Title
- MAMMALIAN GENOME
- Publication Type
- Journal Article
- Abstract
- We have mapped the gene encoding the murine RYK growth factor receptor protein tyrosine kinase by genetic linkage analysis with recombinant inbred strains of mouse. Two distinct Ryk loci (Ryk-1 and Ryk-2) were identified. Ryk-1 mapped to Chromosome (Chr) 9, whereas Ryk-2 mapped to Chr 12. A similar arrangement of RYK-related loci was previously determined in the human. Synteny has already been established between murine Chr 9 in the region of Ryk-1, and human chromosome 3q11-12, the location of the human RYK-1 gene. However, the Ryk-2/RYK-2 loci on murine Chr 12 and human Chr 17p13.3 define a new region of synteny.
- Publisher
- SPRINGER VERLAG
- Keywords
- DOMAIN; MAPS
- Publisher's Version
- https://doi.org/10.1007/BF00352411
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1995-04-01 12:00:00