LIFE AND DEATH DURING LYMPHOCYTE DEVELOPMENT AND FUNCTION - EVIDENCE FOR 2 DISTINCT KILLING MECHANISMS
- Author(s)
- Strasser, A;
- Details
- Publication Year 1995-04,Volume 7,Issue #2,Page 228-234
- Journal Title
- CURRENT OPINION IN IMMUNOLOGY
- Publication Type
- Journal Article
- Abstract
- During their development and after their functional activation most lymphocytes die, either because they fail to receive a survival signal or because they are actively killed. Recent experiments on Bcl-2 and Fas/Apo-1 have provided evidence that these two death processes are subject to distinct genetic control.
- Publisher
- CURRENT BIOLOGY LTD
- Keywords
- PROGRAMMED CELL-DEATH; TUMOR-NECROSIS-FACTOR; BCL-2 PROTOONCOGENE EXPRESSION; MATURE T-CELLS; FAS ANTIGEN; BONE-MARROW; B-CELLS; CAENORHABDITIS-ELEGANS; MEDIATED CYTOTOXICITY; THYMOCYTE APOPTOSIS
- Publisher's Version
- https://doi.org/10.1016/0952-7915(95)80007-7
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1995-04-01 12:00:00