Breast cancer risk and the BRCA1 interacting protein CTIP
Details
Publication Year 2008-11,Volume 112,Issue #2,Page 351-352
Journal Title
BREAST CANCER RESEARCH AND TREATMENT
Publication Type
Journal Article
Abstract
Mutations in BRCA1 predispose to breast cancer. CTIP interacts with BRCA1 and so could also be associated with increased risk. We screened CTIP for germline mutations in 210 probands of breast cancer families including 129 families with no mutations in BRCA1 or BRCA2. No coding variants were detected in CTIP, therefore, it is unlikely to be involved in breast cancer risk.
Publisher
SPRINGER
Keywords
CHECKPOINT CONTROL; DNA-DAMAGE; BINDING; GENE; MUTATIONS; DOMAINS; LEADS
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2008-11-01 12:00:00
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