The network of cytokines, receptors and transcription factors governing the development of dendritic cell subsets
- Details
- Publication Year 2011-08,Volume 2,Issue #8,Page 620-630
- Journal Title
- PROTEIN & CELL
- Publication Type
- Journal Article
- Abstract
- The pathways leading to the development of different dendritic cell (DC) subsets have long been unclear. In recent years, a number of precursors on the route to DC development, both under steady state and inflammatory conditions, have been described, and the nature of these pathways is becoming clearer. In addition, the development of various knockout mouse models and an in vitro system modelling DC development have revealed the role of numerous cytokines and transcription factors that influence DC development. Here, we review recent findings on the factors important in DC development in the context of the developmental pathways that have been described.
- Publisher
- HIGHER EDUCATION PRESS
- Keywords
- BONE-MARROW CULTURES; INTERFERON-PRODUCING CELLS; COLONY-STIMULATING FACTOR; REGULATORY T-CELLS; IN-VIVO; LANGERHANS CELLS; GM-CSF; CROSS-PRESENTATION; FLT3 LIGAND; CONTACT HYPERSENSITIVITY
- Publisher's Version
- https://doi.org/10.1007/s13238-011-1088-0
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2011-08-01 12:00:00