Many Routes to a Micro RNA
Author(s)
Yeo, JHC; Chong, MMW;
Details
Publication Year 2011-11,Volume 63,Issue #11,Page 972-978
Journal Title
IUBMB LIFE
Publication Type
Journal Article
Abstract
Micro RNAs (miRNAs) are similar to 22 nt small RNAs that function as posttranscriptional negative regulators of gene expression. Thousands of these molecules have so far been identified across the metazoan and plant kingdoms. Although most miRNAs share the same biogenesis pathway, numerous noncanonical miRNAs and other small RNAs have also been identified. In this review, we will discuss these alternate small RNA biogenesis pathways as well as recent discoveries of non-miRNA functions of the miRNA biogenesis machinery. This review will focus only on metazoan pathways. (C) 2011 IUBMB IUBMB Life, 63(11): 972-978, 2011
Publisher
WILEY-BLACKWELL
Keywords
C-ELEGANS; MICROPROCESSOR COMPLEX; DROSHA-DGCR8 COMPLEX; MIRNA BIOGENESIS; MOUSE OOCYTES; DICER; DROSOPHILA; PATHWAY; PROTEIN; PIWI
Publisher's Version
https://doi.org/10.1002/iub.524
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2011-11-01 12:00:00
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