Signal-mediated export of proteins from the malaria parasite to the host erythrocyte
- Author(s)
- Marti, M; Baum, J; Rug, M; Tilley, L; Cowman, AF;
- Details
- Publication Year 2005-11-21,Volume 171,Issue #4,Page 587-592
- Journal Title
- JOURNAL OF CELL BIOLOGY
- Publication Type
- Journal Article
- Abstract
- Intracellular parasites from the genus Plasmodium reside and multiply in a variety of cells during their development. After invasion of human erythrocytes, asexual stages from the most virulent malaria parasite, P. falciparum, drastically change their host cell and export remodelling and virulence proteins. Recent data demonstrate that a specific NH2-terminal signal conserved across the genus Plasmodium plays a central role in this export process.
- Publisher
- ROCKEFELLER UNIV PRESS
- Keywords
- FALCIPARUM-INFECTED ERYTHROCYTES; HISTIDINE-RICH PROTEIN; RED-BLOOD-CELLS; PLASMODIUM-FALCIPARUM; MAURERS CLEFTS; MEMBRANE-PROTEINS; SURFACE-ANTIGEN; TRANSMISSION STAGES; TARGETING SIGNAL; RING STAGE
- Publisher's Version
- https://doi.org/10.1083/jcb.200508051
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2005-11-21 12:00:00