Concise review: Hematopoietic stem cells and tissue stem cells: Current concepts and unanswered questions
- Author(s)
- Metcalf, D;
- Details
- Publication Year 2007,Volume 25,Issue #10,Page 2390-2395
- Journal Title
- STEM CELLS
- Publication Type
- Journal Article
- Abstract
- The term hematopoietic stem cells has at times been used to include a miscellany of precursor cells ranging from multipotential self-generating cells to lineage-restricted progenitors with little capacity for self-generation. It is probable that the stem cells of other tissues also vary widely in their multipotentiality and proliferative capacity. This review questions several dogmas regarding the self-generative capacity of various hematopoietic cells, the single episodic origin of hematopoietic cells, and the irreversible nature of progressive mature cell formation in individual hematopoietic lineages.
- Publisher
- ALPHAMED PRESS
- Keywords
- Hematopoietic stem cells; Tissue stem cells
- Publisher's Version
- https://doi.org/10.1634/stemcells.2007-0544
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2007-01-01 12:00:00
Last Modified: 2014-12-23 01:39:02