Protein targeting to destinations of the secretory pathway in the malaria parasite Plasmodium falciparum
- Author(s)
- Tonkin, CJ; Pearce, JA; McFadden, GI; Cowman, AF;
- Details
- Publication Year 2006-08,Volume 9,Issue #4,Page 381-387
- Journal Title
- CURRENT OPINION IN MICROBIOLOGY
- Publication Type
- Journal Article
- Abstract
- The secretory pathway in the malaria parasite Plasmodium falciparum has many unique aspects in terms of protein destinations and trafficking mechanisms. Recently, several exciting insights into protein trafficking within this intracellular parasite have been unveiled: these include signals that are required for targeting of proteins to the red blood cell and the relict plastid (known as the apicoplast); and the elucidation of the pathways of the haemoglobin proteases targeted to the food vacuole. Protein-targeting to the apical organelles in P. falciparum, however, is still not very well understood, but available research offers a tantalising glimpse of the system.
- Publisher
- CURRENT BIOLOGY LTD
- Keywords
- TOXOPLASMA-GONDII; INFECTED ERYTHROCYTES; HOST ERYTHROCYTE; TRAFFICKING; APICOPLAST; MEMBRANE; GOLGI; MECHANISMS; VIRULENCE; COMPLEX
- Publisher's Version
- https://doi.org/10.1016/j.mib.2006.06.015
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2006-08-01 12:00:00