Regulating B-cell activation and survival in response to TLR signals
Details
Publication Year 2007-08,Volume 85,Issue #6,Page 471-475
Journal Title
IMMUNOLOGY AND CELL BIOLOGY
Publication Type
Journal Article
Abstract
Following encounters with microbes, cellular activation programs that involve the control of proliferation and survival are initiated in follicular B cells either via the B-cell receptor in a specific antigen-defined manner, or through Toll-like receptors (TLRs) that recognize specific microbial products. This review summarizes and discusses recent findings that shed light on how the nuclear factor kappa B pathway controls and coordinates B-cell division and survival following TLR4 engagement.
Publisher
NATURE PUBLISHING GROUP
Keywords
NF-KAPPA-B; TRANSCRIPTION FACTORS; CYCLE PROGRESSION; PROTEIN; REL; KINASE; NF-KAPPA-B1; LYMPHOCYTES; PATHWAY; BIM
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2007-08-01 12:00:00
An error has occurred. This application may no longer respond until reloaded. Reload 🗙