Regulating B-cell activation and survival in response to TLR signals
- Author(s)
- Gerondakis, S; Grumont, RJ; Banerjee, A;
- Details
- Publication Year 2007-08,Volume 85,Issue #6,Page 471-475
- Journal Title
- IMMUNOLOGY AND CELL BIOLOGY
- Publication Type
- Journal Article
- Abstract
- Following encounters with microbes, cellular activation programs that involve the control of proliferation and survival are initiated in follicular B cells either via the B-cell receptor in a specific antigen-defined manner, or through Toll-like receptors (TLRs) that recognize specific microbial products. This review summarizes and discusses recent findings that shed light on how the nuclear factor kappa B pathway controls and coordinates B-cell division and survival following TLR4 engagement.
- Publisher
- NATURE PUBLISHING GROUP
- Keywords
- NF-KAPPA-B; TRANSCRIPTION FACTORS; CYCLE PROGRESSION; PROTEIN; REL; KINASE; NF-KAPPA-B1; LYMPHOCYTES; PATHWAY; BIM
- Publisher's Version
- https://doi.org/10.1038/sj.icb.7100097
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2007-08-01 12:00:00