Two roads to death – Bax targets mitochondria by distinct routes before or during apoptotic cell death
- Author(s)
- Dewson, Grant;
- Details
- Publication Year 2015-01-02,Volume 2,Issue #1,Page e974460
- Journal Title
- Mol Cell Oncol
- Publication Type
- Journal Article
- Abstract
- Recent studies have revolutionized our understanding of how the crucial apoptosis effectors Bax and Bak target mitochondria to kill cells. We recently reported that an important determinant of the localization, oligomerization, and apoptotic function of Bax is an interaction with either mitochondrial voltage-dependent anion channel 2 (VDAC2) (in healthy cells) or Bak (in apoptotic cells).1
- Publisher
- Taylor & Francis
- Research Division(s)
- Cell Signalling And Cell Death
- Publisher's Version
- https://doi.org/10.4161/23723556.2014.974460
- Open Access at Publisher's Site
http://www.tandfonline.com/doi/full/10.4161/23723556.2014.974460- NHMRC Grants
- NHMRC/637335,
- ARC Grants
- ARC/FT100100791,
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2016-02-17 04:20:08
Last Modified: 2016-02-17 04:25:45