Killing Lymphoma with Smac-Mimetics: As Easy as ABC?
- Author(s)
- Nachbur, U; Silke, J;
- Details
- Publication Year 2016-04-11,Volume 29,Issue #4,Page 425-7
- Journal Title
- Cancer Cell
- Publication Type
- Journal Article
- Abstract
- Smac-mimetics are compounds that target cellular Inhibitor of APoptosis (cIAP) proteins and induce tumor cell death. In this issue of Cancer Cell, Yang and colleagues (2016) identify cIAPs at the CARD11-MALT1-BCL10 complex in the ABC subtype of diffuse large B cell lymphoma (DLBCL), making this malignancy a prime target for these drugs.
- Publisher
- Cell Press
- Research Division(s)
- Cell Signalling And Cell Death
- PubMed ID
- 27070692
- Publisher's Version
- https://doi.org/10.1016/j.ccell.2016.03.018
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2016-04-28 02:06:58
Last Modified: 2016-05-02 08:39:00