YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfolipids
- Author(s)
- Speciale, G; Jin, Y; Davies, GJ; Williams, SJ; Goddard-Borger, ED;
- Journal Title
- Nat Chem Biol
- Publication Type
- Journal Article
- Abstract
- Sulfoquinovose is produced by photosynthetic organisms at a rate of 1010 tons per annum and is degraded by bacteria as a source of carbon and sulfur. We have identified Escherichia coli YihQ as the first dedicated sulfoquinovosidase and the gateway enzyme to sulfoglycolytic pathways. Structural and mutagenesis studies unveiled the sequence signatures for binding the distinguishing sulfonate residue and revealed that sulfoquinovoside degradation is widespread across the tree of life.
- Publisher
- NPG
- Research Division(s)
- Chemical Biology
- PubMed ID
- 26878550
- Publisher's Version
- https://doi.org/10.1038/nchembio.2023
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2016-03-15 03:47:46
Last Modified: 2018-07-09 03:18:18