Mosquito behaviour change after distribution of bednets results in decreased protection against malaria exposure

Thomsen, EK; Koimbu, G; Pulford, J; Jamea-Maiasa, S; Ura, Y; Keven, JB; Siba, PM; Mueller, I; Hetzel, MW; Reimer, LJ

Author(s): Thomsen, EK; Koimbu, G; Pulford, J; Jamea-Maiasa, S; Ura, Y; Keven, JB; Siba, PM; Mueller, I; Hetzel, MW; Reimer, LJ;
Details: Publication Year 2017-03-01,Volume 215,Issue #5,Page 790-797
Journal Title: Journal of Infectious Diseases
Publication Type: Journal Article
Abstract: BACKGROUND: Behavioural resilience in mosquitoes poses a significant challenge to mosquito control. Although behaviour changes in anopheline vectors have been reported over the last decade, there are no empirical data to suggest they compromise the efficacy of vector control in reducing malaria transmission. METHODS: In this study, we quantified human exposure to both bites and infective bites of a major malaria vector in Papua New Guinea over the course of four years surrounding a nationwide bednet distribution. We also quantified malaria infection prevalence in the human population during the same time period. RESULTS: We observed a shift in mosquito biting to earlier hours of the evening, before individuals are indoors and protected by bednets, followed by a return to pre-intervention biting rates. As a result, net users and non-net users experienced higher levels of transmission than before the intervention. The personal protection provided by a bednet decreased over the study period and was lowest in the adult population, who may be an important reservoir for transmission. Malaria prevalence decreased in only one of three study villages after the distribution. DISCUSSION: This study highlights the necessity of validating and deploying vector control measures targeting outdoor exposure to control and eliminate malaria.
Publisher: OUP
Research Division(s): Population Health And Immunity
PubMed ID: 28007921
Link To PubMed Central Version: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388271/
Publisher's Version: https://doi.org/10.1093/infdis/jiw615
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2017-05-26 03:48:55

Last Modified: 2018-07-05 09:14:59