The evolving world of pseudoenzymes: proteins, prejudice and zombies
- Author(s)
- Eyers, PA; Murphy, JM;
- Details
- Publication Year 2016-11-11,Volume 14,Issue #1,Page 98
- Journal Title
- BMC Biol
- Publication Type
- Journal Article
- Abstract
- Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechanisms with drugs.
- Publisher
- BioMed Central
- Research Division(s)
- Cell Signalling And Cell Death
- PubMed ID
- 27835992
- Publisher's Version
- https://doi.org/10.1186/s12915-016-0322-x
- Open Access at Publisher's Site
http://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0322-x- NHMRC Grants
- NHMRC/1057905, NHMRC/1067289, NHMRC/1105754,
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2016-11-17 01:54:40
Last Modified: 2016-11-17 01:56:36