Malaria: Biology and disease
- Author(s)
- Cowman, AF; Healer, J; Marapana, D; Marsh, K;
- Details
- Publication Year 2016-10-20,Volume 167,Issue #3,Page 610-624
- Journal Title
- Cell
- Publication Type
- Journal Article
- Abstract
- Malaria has been a major global health problem of humans through history and is a leading cause of death and disease across many tropical and subtropical countries. Over the last fifteen years renewed efforts at control have reduced the prevalence of malaria by over half, raising the prospect that elimination and perhaps eradication may be a long-term possibility. Achievement of this goal requires the development of new tools including novel antimalarial drugs and more efficacious vaccines as well as an increased understanding of the disease and biology of the parasite. This has catalyzed a major effort resulting in development and regulatory approval of the first vaccine against malaria (RTS,S/AS01) as well as identification of novel drug targets and antimalarial compounds, some of which are in human clinical trials.
- Publisher
- Cell Press
- Research Division(s)
- Infection And Immunity
- PubMed ID
- 27768886
- Publisher's Version
- https://doi.org/10.1016/j.cell.2016.07.055
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2016-10-25 02:58:25
Last Modified: 2016-10-25 03:39:14