The molecular relationships between apoptosis, autophagy and necroptosis
Journal Title
Semin Cell Dev Biol
Publication Type
Journal Article in press
Abstract
Cells are constantly subjected to a vast range of potentially lethal insults, which may activate specific molecular pathways that have evolved to kill the cell. Cell death pathways are defined partly by their morphology, and more specifically by the molecules that regulate and enact them. As these pathways become more thoroughly characterized, interesting molecular links between them have emerged, some still controversial and others hinting at the physiological and pathophysiological roles these death pathways play. We describe specific molecular programs controlling cell death, with a focus on some of the distinct features of the pathways and the molecular links between them.
Publisher
Elsevier
Research Division(s)
Cell Signalling And Cell Death
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2015-03-06 11:41:46
Last Modified: 2015-05-12 09:33:30
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