IL-17 cuts to the chase in colon cancer
- Author(s)
- Ernst, M; Putoczki, T;
- Details
- Publication Year 2014-12-18,Volume 41,Issue #6,Page 880-2
- Journal Title
- Immunity
- Publication Type
- Journal Article
- Abstract
- Although interleukin-17A (IL-17A) facilitates colon cancer development, its target cells remain elusive. In this issue of Immunity, Wang et al. (2014) now demonstrate that IL-17A receptors on the intestinal epithelium promote progression of APC mutant adenomas associated with IL-6 expression and that IL-17A confers chemotherapy resistance.
- Publisher
- Cell Press
- Research Division(s)
- Cell Signalling And Cell Death; Inflammation
- Publisher's Version
- https://doi.org/10.1016/j.immuni.2014.12.004
- Terms of Use/Rights Notice
- Copyright © 2014 Elsevier Inc. All rights reserved.
Creation Date: 2014-12-23 09:57:14
Last Modified: 2014-12-23 10:02:34