Plasmodium falciparum and Plasmodium vivax genotypes and efficacy of intermittent preventive treatment in Papua New Guinea
- Author(s)
- Barnadas, C; Senn, N; Iga, J; Timinao, L; Javati, S; Malau, E; Rarau, P; Reeder, JC; Siba, P; Karunajeewa, H; Zimmerman, PA; Davis, TM; Mueller, I;
- Details
- Publication Year 2014-08-25,Volume 58,Issue #11,Page 6958-6961
- Journal Title
- Antimicrob Agents Chemother
- Publication Type
- Journal Article
- Abstract
- Intermittent preventive treatment of infants (IPTi) reduces early-childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimalarial drugs in case management, there are few equivalent data relating to their protective efficacy when used as IPTi. The present data from an IPTi trial in Papua New Guinea demonstrate how these markers can predict protective efficacy of IPTi for both Plasmodium falciparum and vivax.
- Publisher
- American Society for Microbiology
- Research Division(s)
- Infection And Immunity
- Publisher's Version
- https://doi.org/10.1128/aac.03323-14
- NHMRC Grants
- NHMRC/1043345,
- Terms of Use/Rights Notice
- Copyright © 2014, American Society for Microbiology. All Rights Reserved.
Creation Date: 2014-09-12 02:01:39