Differentiation and diversity of subsets in group 1 innate lymphoid cells
Author(s)
Seillet, C; Belz, GT;
Details
Publication Year 2016-01,Volume 129,Issue #1,Page 228-242
Journal Title
Int Immunol
Publication Type
Journal Article
Abstract
NK cells were first identified in 1975 and represent the prototypical group I innate lymphoid cell (ILC). More recently, the discovery of new members of the ILC family have highlighted the complexity of this innate lymphoid lineage. Importantly, it has been recognized that different subsets exist within the group I ILC that have potential roles in mediating immune protection and immunosurveillance, and in regulating tissue homeostasis and inflammation. Here, we review the developmental relationships between the different group I ILC that have been identified to date and discuss how heterogeneity within this expanding family may have arisen.
Publisher
OUP
Research Division(s)
Molecular Immunology
PubMed ID
26346810
NHMRC Grants
NHMRC/1027472NHMRC/1047903
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2015-09-24 02:12:28
Last Modified: 2016-01-13 10:11:47
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