Colony-stimulating factor and inhibitor levels in acute granulocytic leukemia.
- Author(s)
- Metcalf, D; Chan, SH; Gunz, FW; Vincent, P; Ravich, RB;
- Details
- Publication Year 1971-08,Volume 38,Issue #2,Page 143-52
- Journal Title
- Blood
- Publication Type
- Journal Article
- Abstract
- Assays were performed on bone marrow colony-stimulating-factor (CSF) levels in the serum and urine of 33 patients with acute granulocytic and myelomonocytic leukemia. Of 251 serum samples, 30% showed elevated CSF levels as did 53% of 1422 urines tested. Levels of serum inhibitors of colony formation were abnormally low or undetectable in 57% of sera from leukemic patients. Patients in relapse were unable to respond to infections by developing high serum CSF levels and low serum-inhibitor levels were more common in patients with a short survival time and in some types of patient during relapses.
- PubMed ID
- 5283026
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2015-07-23 08:59:24
Last Modified: 2015-10-29 11:27:42