Malaria epidemiology and control within the International Centers of Excellence for Malaria Research
- Author(s)
- Moss, WJ; Dorsey, G; Mueller, I; Laufer, MK; Krogstad, DJ; Vinetz, JM; Guzman, M; Rosas-Aguirre, AM; Herrera, S; Arevalo-Herrera, M; Chery, L; Kumar, A; Mohapatra, PK; Ramanathapuram, L; Srivastava, HC; Cui, L; Zhou, G; Parker, DM; Nankabirwa, J; Kazura, JW; International Centers of Excellence for Malaria Research,;
- Details
- Publication Year 2015-08-10,Volume 93,Issue #3 Suppl,Page 5-15
- Journal Title
- American Journal of Tropical Medicine and Hygiene
- Publication Type
- Journal Article
- Abstract
- Understanding the epidemiological features and metrics of malaria in endemic populations is a key component to monitoring and quantifying the impact of current and past control efforts to inform future ones. The International Centers of Excellence for Malaria Research (ICEMR) has the opportunity to evaluate the impact of malaria control interventions across endemic regions that differ in the dominant Plasmodium species, mosquito vector species, resistance to antimalarial drugs and human genetic variants thought to confer protection from infection and clinical manifestations of plasmodia infection. ICEMR programs are conducting field studies at multiple sites with the aim of generating standardized surveillance data to improve the understanding of malaria transmission and to monitor and evaluate the impact of interventions to inform malaria control and elimination programs. In addition, these epidemiological studies provide a vast source of biological samples linked to clinical and environmental "meta-data" to support translational studies of interactions between the parasite, human host, and mosquito vector. Importantly, epidemiological studies at the ICEMR field sites are integrated with entomological studies, including the measurement of the entomological inoculation rate, human biting index, and insecticide resistance, as well as studies of parasite genetic diversity and antimalarial drug resistance.
- Publisher
- The American Society of Tropical Medicine and Hygiene
- Research Division(s)
- Population Health And Immunity
- PubMed ID
- 26259946
- Publisher's Version
- https://doi.org/10.4269/ajtmh.15-0006
- Open Access at Publisher's Site
- http://www.ajtmh.org/content/93/3_Suppl/5.long
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2015-08-21 12:29:31
Last Modified: 2019-04-01 09:14:22