Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4(+) T cells
- Author(s)
- Sollid, LM; Tye-Din, JA; Qiao, SW; Anderson, RP; Gianfrani, C; Koning, F;
- Journal Title
- Immunogenetics
- Publication Type
- Journal Article in press
- Abstract
- Celiac disease is caused by an abnormal intestinal T cell response to cereal gluten proteins. The disease has a strong human leukocyte antigen (HLA) association, and CD4(+) T cells recognizing gluten epitopes presented by disease-associated HLA-DQ allotypes are considered to be drivers of the disease. This paper provides an update of the currently known HLA-DQ restricted gluten T cell epitopes with their names and sequences.
- Publisher
- Springer
- Research Division(s)
- Immunology
- PubMed ID
- 31735991
- Publisher's Version
- https://doi.org/10.1007/s00251-019-01141-w
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2019-11-20 02:45:22
Last Modified: 2019-11-21 10:16:36