Emerging roles for Interleukin-11 in disease
- Author(s)
- Nguyen, PM; Abdirahman, SM; Putoczki, TL;
- Journal Title
- Growth Factors
- Publication Type
- Journal Article in press
- Abstract
- Interleukin (IL)-11 belongs to the IL-6 family of cytokines, discovered over 30 years ago. While early studies focused on the ability of IL-11 to stimulate megakaryocytopoiesis, the importance of this cytokine to inflammatory disease and cancers is only just beginning to be uncovered. This review outlines recent advances in our understanding of IL-11 biology, and highlights the development of novel therapeutics with the potential for clinical targeting of signaling by this cytokine in multiple diseases.
- Publisher
- Taylor & Francis
- Research Division(s)
- Personalised Oncology
- PubMed ID
- 31161823
- Publisher's Version
- https://doi.org/10.1080/08977194.2019.1620227
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2019-06-14 09:37:01
Last Modified: 2019-06-14 11:26:39