Emerging roles for Interleukin-11 in disease
Journal Title
Growth Factors
Publication Type
Journal Article in press
Abstract
Interleukin (IL)-11 belongs to the IL-6 family of cytokines, discovered over 30 years ago. While early studies focused on the ability of IL-11 to stimulate megakaryocytopoiesis, the importance of this cytokine to inflammatory disease and cancers is only just beginning to be uncovered. This review outlines recent advances in our understanding of IL-11 biology, and highlights the development of novel therapeutics with the potential for clinical targeting of signaling by this cytokine in multiple diseases.
Publisher
Taylor & Francis
WEHI Research Division(s)
Personalised Oncology
PubMed ID
31161823
Rights Notice
Refer to copyright notice on published article.


Creation Date: 2019-06-14 09:37:01
Last Modified: 2019-06-14 11:26:39
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