Primary mucinous ovarian neoplasms rarely exhibit a germ cell histogenesis
- Author(s)
- Kommoss, FK; Cheasley, D; Wakefield, MJ; Scott, CL; Campbell, IG; Gorringe, K; Gilks, CB;
- Details
- Publication Year 2021-03,Volume 78,Issue #4,Page 640-642
- Journal Title
- Histopathology
- Publication Type
- Journal article
- Abstract
- Recently, genetic analyses of primary mucinous ovarian tumours (MOT) have considerably enhanced our understanding of the biology of such neoplasms, supporting a progressive model of carcinogenesis from benign/borderline tumours to carcinomas. Nevertheless, the histogenesis of these neoplasms remains a subject of discussion and several cell types of origin have been proposed; a proportion of these tumours are associated with Brenner (transitional cell) tumours, therefore some are believed to be derived from metaplastic mucinous epithelium lining cystic transitional cell nests (Walthard rests).
- Publisher
- Wiley
- Research Division(s)
- Cancer Biology And Stem Cells; Bioinformatics
- PubMed ID
- 33151585
- Publisher's Version
- https://doi.org/10.1111/his.14297
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2021-02-01 12:05:15
Last Modified: 2021-10-20 10:55:39