The interplay of leukemia cells and the bone marrow microenvironment
Details
Publication Year 2018-02-27,Volume 131,Issue #14,Page 1507-1511
Journal Title
Blood
Publication Type
Journal Article
Abstract
The interplay of cancer cells and surrounding stroma is critical in disease progression. This is particularly evident in hematological malignancies that infiltrate the bone marrow and peripheral lymphoid organs. Despite clear evidence for the existence of these interactions, the precise repercussions on the growth of leukemic cells are poorly understood. Recent development of novel imaging technology and preclinical disease models have advanced our comprehension of leukemia-microenvironment crosstalk and have potential implications for development of novel treatment options.
Publisher
ASH
Research Division(s)
Immunology
PubMed ID
29487069
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2018-03-27 09:58:22
Last Modified: 2018-07-09 02:10:33
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