The interplay of leukemia cells and the bone marrow microenvironment
- Author(s)
- Duarte, D; Hawkins, ED; Lo Celso, C;
- Details
- Publication Year 2018-02-27,Volume 131,Issue #14,Page 1507-1511
- Journal Title
- Blood
- Publication Type
- Journal Article
- Abstract
- The interplay of cancer cells and surrounding stroma is critical in disease progression. This is particularly evident in hematological malignancies that infiltrate the bone marrow and peripheral lymphoid organs. Despite clear evidence for the existence of these interactions, the precise repercussions on the growth of leukemic cells are poorly understood. Recent development of novel imaging technology and preclinical disease models have advanced our comprehension of leukemia-microenvironment crosstalk and have potential implications for development of novel treatment options.
- Publisher
- ASH
- Research Division(s)
- Immunology
- PubMed ID
- 29487069
- Publisher's Version
- https://doi.org/10.1182/blood-2017-12-784132
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2018-03-27 09:58:22
Last Modified: 2018-07-09 02:10:33