Whole genome analysis of a schistosomiasis-transmitting freshwater snail
Journal Title
Nat Commun
Publication Type
Journal Article
Abstract
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
WEHI Research Division(s)
Bioinformatics
PubMed ID
28508897
Open Access at Publisher's Site
http://www.nature.com/articles/ncomms15451
Rights Notice
Refer to copyright notice on published article.


Creation Date: 2018-01-15 09:30:19
Last Modified: 2018-01-15 10:09:29
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