Methods for studying TNF-mediated necroptosis in cultured cells
- Author(s)
- LIU, Z; Silke, J; Hildebrand, JM;
- Journal Title
- Methods in Molecular Biology
- Publication Type
- Journal Article
- Abstract
- Necroptosis is a caspase-independent form of programmed cell death that is induced by a variety of different signalling cascades-all culminating in the activation of the pseudokinase mixed lineage kinase domain-like (MLKL). TNF-induced necroptosis is the most intensively studied of these pathways. Here we describe reagents and cell-based techniques that can be used to investigate TNF-mediated necroptosis in the lab.
- Publisher
- Springer
- Research Division(s)
- Cell Signalling And Cell Death
- PubMed ID
- 30136229
- Publisher's Version
- https://doi.org/10.1007/978-1-4939-8754-2_5
- NHMRC Grants
- NHMRC/1105023, NHMRC/1107149, NHMRC/1142669,
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2018-08-27 09:10:43
Last Modified: 2018-08-27 09:25:02