Minimal variation of the plasma lipidome after delayed processing of neonatal cord blood
- Author(s)
- Wentworth, JM; Bediaga, NG; Penno, MAS; Bandala-Sanchez, E; Kanojia, KN; Kouremenos, KA; Couper, JJ; Harrison, LC; Endia Study Group,;
- Details
- Publication Year 2018,Volume 14,Issue #10,Page 130
- Journal Title
- Metabolomics
- Publication Type
- Journal Article
- Abstract
- Background: Cord blood lipids are potential disease biomarkers. We aimed to determine if their concentrations were affected by delayed blood processing. Method: Refrigerated cord blood from six healthy newborns was centrifuged every 12 h for 4 days. Plasma lipids were analysed by liquid chromatography/mass spectroscopy. Results: Of 262 lipids identified, only eight varied significantly over time. These comprised three dihexosylceramides, two phosphatidylserines and two phosphatidylethanolamines whose relative concentrations increased and one sphingomyelin that decreased. Conclusion: Delay in separation of plasma from refrigerated cord blood has minimal effect overall on the plasma lipidome. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
- Publisher
- Springer
- Research Division(s)
- Population Health And Immunity
- Publisher's Version
- https://doi.org/10.1007/s11306-018-1434-9
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2018-10-11 04:23:20
Last Modified: 2018-10-12 04:01:08