Minimal variation of the plasma lipidome after delayed processing of neonatal cord blood
Details
Publication Year 2018,Volume 14,Issue #10,Page 130
Journal Title
Metabolomics
Publication Type
Journal Article
Abstract
Background: Cord blood lipids are potential disease biomarkers. We aimed to determine if their concentrations were affected by delayed blood processing. Method: Refrigerated cord blood from six healthy newborns was centrifuged every 12 h for 4 days. Plasma lipids were analysed by liquid chromatography/mass spectroscopy. Results: Of 262 lipids identified, only eight varied significantly over time. These comprised three dihexosylceramides, two phosphatidylserines and two phosphatidylethanolamines whose relative concentrations increased and one sphingomyelin that decreased. Conclusion: Delay in separation of plasma from refrigerated cord blood has minimal effect overall on the plasma lipidome. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
Publisher
Springer
Research Division(s)
Population Health And Immunity
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Creation Date: 2018-10-11 04:23:20
Last Modified: 2018-10-12 04:01:08
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