Ion Man: GSDMD punches pores to knock out cGAS
- Author(s)
- Feltham, R; Vince, JE;
- Details
- Publication Year 2018-09-18,Volume 49,Issue #3,Page 379-381
- Journal Title
- Immunity
- Publication Type
- Journal Article
- Abstract
- The pore-forming protein GSDMD promotes cytokine release and induces pyroptotic cell death. In this issue of Immunity, Banerjee et al. (2018) document how GSDMD triggers potassium efflux to inhibit cGAS-STING and prevent damaging interferon production after bacterial infection.
- Publisher
- Cell Press
- Research Division(s)
- Inflammation
- PubMed ID
- 30231975
- Publisher's Version
- https://doi.org/10.1016/j.immuni.2018.08.026
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2018-10-11 04:23:14
Last Modified: 2018-10-12 03:00:43