Keeping memories alive.
- Author(s)
- Belz, GT; Cretney, E;
- Journal Title
- Frontiers in Immunology
- Publication Type
- Journal Article
- Abstract
- Memory T cells confer immune protection against a diverse range of pathogens. The quantity and quality of responding memory T cells depends on a number of factors including cytokines, recognition of pathogen-derived MHC complexes, and costimulatory molecules. Integration of these signals ensures that T cell responses are tightly regulated. Delineating the mechanisms that regulate the differentiation, establishment, and maintenance of memory T cells is fundamental to life-long immune protection and for engineering of effective T cell-based vaccines.
- Publisher
- Frontiers Media
- Keywords
- Memory T cells
- Research Division(s)
- Molecular Immunology
- Publisher's Version
- https://doi.org/10.3389/fimmu.2013.00021
- Open Access at Publisher's Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561740/- Terms of Use/Rights Notice
- Copyright © 2013 Belz and Cretney. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
Creation Date: 2013-01-01 12:00:00