Vaccination with Conserved Regions of Erythrocyte-Binding Antigens Induces Neutralizing Antibodies against Multiple Strains of Plasmodium falciparum.
- Author(s)
- Healer, J; Thompson, JK; Riglar, DT; Wilson, DW; Chiu, YH; Miura, K; Chen, L; Hodder, AN; Long, CA; Hansen, DS; Baum, J; Cowman, AF;
- Details
- Publication Year 2013,Volume 8,Issue #9,Page e72504
- Journal Title
- PLoS One
- Publication Type
- Journal Article
- Abstract
- A highly effective vaccine against Plasmodium falciparum malaria should induce potent, strain transcending immunity that broadly protects against the diverse population of parasites circulating globally. We aimed to identify vaccine candidates that fulfill the criteria.
- Publisher
- Public Library of Science
- Keywords
- Vaccines ; Malaria ; Protein expression ; Merozoites ; Malarial parasites ; Plasmodium ; Antibodies ; Red blood cells
- Research Division(s)
- Infection And Immunity
- Publisher's Version
- https://doi.org/10.1371/journal.pone.0072504
- Open Access at Publisher's Site
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769340/
- Terms of Use/Rights Notice
- Copyright: © 2013 Healer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Creation Date: 2013-01-01 12:00:00