Flow cytometric analysis of STAT phosphorylation.
Author(s)
Murphy, J; Goldberg, GL;
Journal Title
Methods in Molecular Biology
Publication Type
Journal Article
Abstract
Flow cytometry can be used to study STAT phosphorylation on a per cell basis. Cells are fixed, permeablized, and stained with antibodies that specifically bind to the phosphorylated form of the STAT protein. This allows the tyrosine phosphorylation of a single STAT to be studied within a heterogeneous cell population and/or the phosphorylation of several STATs within the one cell type.
Publisher
Springer
Keywords
STAT phosphorylation ; Flow cytometry ; Phospho-flow
Research Division(s)
Inflammation
Terms of Use/Rights Notice
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Creation Date: 2013-01-01 12:00:00
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