Responding to R-spondin: slit2 potentiates intestinal regeneration
Author(s)
Phesse, TJ; Sansom, OJ;
Details
Publication Year 2013-11-07, Volume 13, Issue #5, Page 512-4
Journal Title
Cell stem cell
Publication Type
Journal Article
Abstract
Gastrointestinal toxicity of chemoradiotherapy treatment in late-stage cancer patients limits tolerable doses and effectiveness of treatments. Zhou and colleagues in Nature (Zhou et al., 2013) suggest that activating Robo/Slit signaling in concert with R-Spondin potentiates Wnt signaling in intestinal stem cells and drives successful intestinal regeneration and recovery.
Publisher
Cell Press
WEHI Research Division(s)
Cell Signalling And Cell Death
Rights Notice
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Creation Date: 2014-04-16 08:43:44
Last Modified: 0001-01-01 12:00:00
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