Obesity is associated with retinopathy and macrovascular disease in type 1 diabetes
- Author(s)
- Price, SA; Gorelik, A; Fourlanos, S; Colman, PG; Wentworth, JM;
- Details
- Publication Year 2014,Volume 8,Issue #2,Page e178-82
- Journal Title
- Obes Res Clin Pract
- Publication Type
- Journal Article
- Abstract
- Excessive body weight is increasingly seen in type 1 diabetes but its impact is debated. To address this uncertainty, we aimed to determine the association between excess body weight and the macro- and microvascular complications of type 1 diabetes. We identified 501 adults with type 1 diabetes attending an Australian hospital clinic and extracted their clinical and biochemical data from our patient management database. In both men and women, obesity (BMI > 30 kg/m(2)) was the predominant risk factor for retinopathy and cardiovascular disease despite similar HbA1c and increased use of cardioprotective drugs compared to non-obese patients. Obesity was associated with albuminuria in women, but not renal impairment or neuropathy in either sex. We conclude that obesity in type 1 diabetes may promote retinopathy and macrovascular disease. Future trials to determine the effect of weight loss on type 1 diabetes in obese people are needed.
- Publisher
- Elsevier
- Research Division(s)
- Molecular Medicine
- Publisher's Version
- https://doi.org/10.1016/j.orcp.2013.03.007
- Terms of Use/Rights Notice
- Copyright © 2013 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.
Creation Date: 2014-06-06 08:31:26