tidybulk: an R tidy framework for modular transcriptomic data analysis
- Author(s)
- Mangiola, S; Molania, R; Dong, R; Doyle, MA; Papenfuss, AT;
- Details
- Publication Year 2021-01-22,Volume 22,Issue #1,Page 42
- Journal Title
- Genome Biology
- Abstract
- Recently, efforts have been made toward the harmonization of transcriptomic data structures and workflows using the concept of data tidiness, to facilitate modularisation. We present tidybulk, a modular framework for bulk transcriptional analyses that introduces a tidy transcriptomic data structure paradigm and analysis grammar. Tidybulk covers a wide variety of analysis procedures and integrates a large ecosystem of publicly available analysis algorithms under a common framework. Tidybulk decreases coding burden, facilitates reproducibility, increases efficiency for expert users, lowers the learning curve for inexperienced users, and bridges transcriptional data analysis with the tidyverse. Tidybulk is available at R/Bioconductor bioconductor.org/packages/tidybulk .
- Publisher
- BMC
- Research Division(s)
- Bioinformatics
- PubMed ID
- 33482892
- Publisher's Version
- https://doi.org/10.1186/s13059-020-02233-7
- Open Access at Publisher's Site
https://doi.org/10.1186/s13059-020-02233-7- NHMRC Grants
- NHMRC/1054618,
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2021-03-09 08:05:31
Last Modified: 2021-03-09 08:13:51