Death by differentiation: CD4(+) T cells kick out suspicious stem cells
Details
Publication Year 2022-05-05,Volume 29,Issue #5,Page 655-656
Journal Title
Cell Stem Cell
Abstract
Antigen presentation is typically regarded as the domain of immune cells such as dendritic cells and B cells. Hernandez-Malmierca et al. (2022) upend this notion by observing that hematopoietic stem and progenitor cells process and present antigen via major histocompatibility class II as a means of CD4(+) T cell-mediated immune surveillance.
Publisher
Cell Press
Keywords
Antigen Presentation; B-Lymphocytes; *CD4-Positive T-Lymphocytes; Dendritic Cells; *Histocompatibility Antigens Class II; Stem Cells
WEHI Research Division(s)
Immunology
PubMed ID
35523132
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2022-05-11 10:40:10
Last Modified: 2022-05-11 11:09:59
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