Death by differentiation: CD4(+) T cells kick out suspicious stem cells
- Author(s)
- Tomei, S; Audiger, C; Naik, SH;
- Details
- Publication Year 2022-05-05,Volume 29,Issue #5,Page 655-656
- Journal Title
- Cell Stem Cell
- Abstract
- Antigen presentation is typically regarded as the domain of immune cells such as dendritic cells and B cells. Hernandez-Malmierca et al. (2022) upend this notion by observing that hematopoietic stem and progenitor cells process and present antigen via major histocompatibility class II as a means of CD4(+) T cell-mediated immune surveillance.
- Publisher
- Cell Press
- Keywords
- Antigen Presentation; B-Lymphocytes; *CD4-Positive T-Lymphocytes; Dendritic Cells; *Histocompatibility Antigens Class II; Stem Cells
- Research Division(s)
- Immunology
- PubMed ID
- 35523132
- Publisher's Version
- https://doi.org/10.1016/j.stem.2022.04.013
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2022-05-11 10:40:10
Last Modified: 2022-05-11 11:09:59