Mental Health During Late Pregnancy and Postpartum in Mothers With and Without Type 1 Diabetes: The ENDIA Study

Hall, M; Oakey, H; Penno, MAS; McGorm, K; Anderson, AJ; Ashwood, P; Colman, PG; Craig, ME; Davis, EA; Harris, M; Harrison, LC; Haynes, A; Morbey, C; Sinnott, RO; Soldatos, G; Vuillermin, PJ; Wentworth, JM; Thomson, RL; Couper, JJ; ENDIA Study Group

Author(s): Hall, M; Oakey, H; Penno, MAS; McGorm, K; Anderson, AJ; Ashwood, P; Colman, PG; Craig, ME; Davis, EA; Harris, M; Harrison, LC; Haynes, A; Morbey, C; Sinnott, RO; Soldatos, G; Vuillermin, PJ; Wentworth, JM; Thomson, RL; Couper, JJ; ENDIA Study Group;
Details: Publication Year 2022-02-02,Volume 45,Issue #5,Page 1082-1090
Journal Title: Diabetes Care
Abstract: OBJECTIVE: Pregnancy and type 1 diabetes are each associated with increased anxiety and depression, but the combined impact on well-being is unresolved. We compared the mental health of women with and without type 1 diabetes during pregnancy and postpartum and examined the relationship between mental health and glycemic control. RESEARCH DESIGN AND METHODS: Participants were women enrolled from 2016 to 2020 in the Environmental Determinants of Islet Autoimmunity (ENDIA) study, a pregnancy to birth prospective cohort following children with a first-degree relative with type 1 diabetes. Edinburgh Postnatal Depression Scale (EPDS) and Perceived Stress Scale (PSS) were completed during the third trimester (T3) (median [interquartile range] 34 [32, 36] weeks) and postpartum (14 [13, 16] weeks) by 737 women (800 pregnancies) with (n = 518) and without (n = 282) type 1 diabetes. RESULTS: EPDS and PSS scores did not differ between women with and without type 1 diabetes during T3 and postpartum. EPDS scores were marginally higher in T3: predicted mean (95% CI) 5.7 (5.4, 6.1) than postpartum: 5.3 (5.0, 5.6), independent of type 1 diabetes status (P = 0.01). HbA1c levels in type 1 diabetes were 6.3% [5.8, 6.9%] in T3 and did not correlate with EPDS or PSS scores. Reported use of psychotropic medications was similar in women with (n = 44 of 518 [8%]) and without type 1 diabetes (n = 17 of 282 [6%]), as was their amount of physical activity. CONCLUSIONS: Overall, mental health in late pregnancy and postpartum did not differ between women with and without type 1 diabetes, and mental health scores were not correlated with glycemic control.
Publisher: ADA
Research Division(s): Population Health And Immunity
PubMed ID: 35107582
Publisher's Version: https://doi.org/10.2337/dc21-2335
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2023-02-24 09:21:04

Last Modified: 2023-02-24 09:25:29