IFNγ: Priming for death
- Author(s)
- Vince, JE;
- Journal Title
- Journal of Cell Biology
- Abstract
- TNF signaling does not result in cell death unless multiple inhibitory signals are overcome, which can be accomplished by simultaneous signaling through IFNγ. In this issue, Deng and colleagues (http://doi.org/10.1083/jcb.202305026) dissect the mechanisms by which IFNγ signaling combines with TNF to mediate cell death through caspase-8, discussed by James E. Vince.
- Publisher
- RUP
- Keywords
- *Cell Death; *Signal Transduction; *Interferon-gamma/physiology; Caspase 8/physiology; Tumor Necrosis Factors/physiology
- Research Division(s)
- Inflammation
- PubMed ID
- 38329462
- Publisher's Version
- https://doi.org/10.1083/jcb.202401127
- Open Access at Publisher's Site
https://doi.org/10.1083/jcb.202401127- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2024-02-29 09:02:04
Last Modified: 2024-02-29 09:15:01