Diagnosing and characterizing inflammatory myopathies at an Australian tertiary public hospital: Resource utilization and direct healthcare costs

Huang, V; Ciciriello, S; Nikpour, M; Oon, S; Day, J

Author(s): Huang, V; Ciciriello, S; Nikpour, M; Oon, S; Day, J;
Details: Publication Year 2024-04,Volume 27,Issue #4,Page e15153
Journal Title: International Journal of Rheumatic Diseases
Abstract: AIM: To determine the direct health service costs and resource utilization associated with diagnosing and characterizing idiopathic inflammatory myopathies (IIMs), and to assess for limitations and diagnostic delay in current practice. METHODS: A retrospective, single-center cohort analysis of all patients diagnosed with IIMs between January 2012 and December 2021 in a large tertiary public hospital was conducted. Demographics, resource utilization and costs associated with diagnosing IIM and characterizing disease manifestations were identified using the hospital's electronic medical record and Health Intelligence Unit, and the Medicare Benefits Schedule. RESULTS: Thirty-eight IIM patients were identified. IIM subtypes included dermatomyositis (34.2%), inclusion body myositis (18.4%), immune-mediated necrotizing myopathy (18.4%), polymyositis (15.8%), and anti-synthetase syndrome (13.2%). The median time from symptom onset to diagnosis was 212 days (IQR: 118-722), while the median time from hospital presentation to diagnosis was 30 days (8-120). Seventy-six percent of patients required emergent hospitalization during their diagnosis, with a median length of stay of 8 days (4-15). The average total cost of diagnosing IIM was $15 618 AUD (STD: 11331) per patient. Fifty percent of patients underwent both MRI and EMG to identify affected muscles, 10% underwent both pan-CT and PET-CT for malignancy detection, and 5% underwent both open surgical and percutaneous muscle biopsies. Autoimmune serology was unnecessarily repeated in 37% of patients. CONCLUSION: The diagnosis of IIMs requires substantial and costly resource use; however, our study has identified potential limitations in current practice and highlighted the need for streamlined diagnostic algorithms to improve patient outcomes and reduce healthcare-related economic burden.
Publisher: Wiley
Keywords: Humans; Retrospective Studies; *Myositis/diagnosis/economics/therapy; Male; Female; Middle Aged; *Tertiary Care Centers/economics; *Hospitals, Public/economics; *Hospital Costs; Aged; Adult; Health Resources/statistics & numerical data/economics; Health Care Costs; Delayed Diagnosis/economics; Predictive Value of Tests; Time Factors; Australia; direct cost; healthcare resource; inflammatory myopathy; myositis; retrospective
Research Division(s): Inflammation
PubMed ID: 38661316
Publisher's Version: https://doi.org/10.1111/1756-185x.15153
Open Access at Publisher's Site: https://doi.org/10.1111/1756-185X.15153
Terms of Use/Rights Notice: Refer to copyright notice on published article.
Documents: Int J of Rheum Dis - 2024 - Huang - Diagnosing and characterizing inflammatory myopathies at an Australian tertiary public.pdf - (2.62MB, application/pdf)

Creation Date: 2024-05-08 10:06:36

Last Modified: 2024-05-08 10:31:13