Mapping where and when necroptotic cell death occurs in disease
- Author(s)
- Samson, AL; Murphy, JM;
- Details
- Publication Year 2024-06-04,Volume 31,Issue #7,Page 833-835
- Journal Title
- Cell Death & Differentiation
- Abstract
- A series of recent studies have established where the necroptosis machinery - RIPK1, RIPK3, MLKL, ZBP1 and Caspase-8 - occur and are activated in mouse and human tissues, and how ZBP1 splicing might regulate necroptosis. These studies highlight the importance of mapping necroptosis spatially to understand how pathway dysregulation can lead to disease.
- Publisher
- Springer Nature
- Keywords
- Humans; *Necroptosis; Animals; Cell Death
- Research Division(s)
- Inflammation
- PubMed ID
- 38834666
- Publisher's Version
- https://doi.org/10.1038/s41418-024-01318-1
- Open Access at Publisher's Site
https://doi.org/10.1038/s41418-024-01318-1- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2024-07-26 09:30:27
Last Modified: 2024-07-26 09:44:39