Increased fatty acid production and macrophage-driven inflammation as key drivers of severe respiratory disease
- Author(s)
- Eriksson, EM; Mueller, I;
- Details
- Publication Year 2025-03,Volume 103,Issue #3,Page 224-227
- Journal Title
- Immunology & Cell Biology
- Abstract
- In this article, we discuss a recent article by Jia et al., where high OLAH expression was detected in severe and fatal respiratory disease which was associated with a number of processes and responses. These include high abundance of oleic acid, excessive cytokine release, high viral titres and lipid droplets and increased presence of lung-associated innate cells.
- Publisher
- Wiley
- Keywords
- Humans; *Inflammation/immunology; *Macrophages/immunology/metabolism; *Fatty Acids/metabolism; Animals; Cytokines/metabolism; fatty acid production; macrophage‐driven inflammation; severe respiratory disease
- Research Division(s)
- Infection and Global Health
- PubMed ID
- 40047400
- Publisher's Version
- https://doi.org/10.1111/imcb.12852
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2025-05-29 02:41:18
Last Modified: 2025-05-29 02:41:49